Berdai Mohamed Adnane, Labib Smael, Harandou Mustapha
Obstetric and Pediatric Intensive Care Unit, University Hospital Hassan II, Fez, Morocco.
Pan Afr Med J. 2016 Sep 14;25:5. doi: 10.11604/pamj.2016.25.5.6616. eCollection 2016.
Recent large use of magnesium in the obstetric population should incite anesthesiologists to control its side effects and drugs interactions. We report a case of a 30-year-old woman, with severe preeclampsia and HELLP syndrome, receiving sulfate magnesium and nicardipine, who underwent a cesarean section under general anesthesia. She developed a prolonged and deep neuromuscular blockade, which was antagonized three hours later with neostigmine. In case of therapeutic hypermagnesaemia, non-depolarizing relaxants must be used in reduced doses, and at increased time intervals, with appropriate neuromuscular monitoring.
近期产科人群中大量使用镁剂应促使麻醉医生控制其副作用及药物相互作用。我们报告一例30岁患有重度子痫前期和HELLP综合征的女性，在接受硫酸镁和尼卡地平治疗期间，在全身麻醉下接受剖宫产手术。她出现了长时间的深度神经肌肉阻滞，三小时后用新斯的明进行了拮抗。在治疗性高镁血症的情况下，必须减少非去极化肌松药的剂量，并延长给药间隔时间，并进行适当的神经肌肉监测。
