硫酸镁诱发的先兆子痫患者的长时间神经肌肉阻滞。
Prolonged neuromuscular block in a preeclamptic patient induced by magnesium sulfate.
作者信息
Berdai Mohamed Adnane, Labib Smael, Harandou Mustapha
机构信息
Obstetric and Pediatric Intensive Care Unit, University Hospital Hassan II, Fez, Morocco.
出版信息
Pan Afr Med J. 2016 Sep 14;25:5. doi: 10.11604/pamj.2016.25.5.6616. eCollection 2016.
Abstract
Recent large use of magnesium in the obstetric population should incite anesthesiologists to control its side effects and drugs interactions. We report a case of a 30-year-old woman, with severe preeclampsia and HELLP syndrome, receiving sulfate magnesium and nicardipine, who underwent a cesarean section under general anesthesia. She developed a prolonged and deep neuromuscular blockade, which was antagonized three hours later with neostigmine. In case of therapeutic hypermagnesaemia, non-depolarizing relaxants must be used in reduced doses, and at increased time intervals, with appropriate neuromuscular monitoring.
摘要
近期产科人群中大量使用镁剂应促使麻醉医生控制其副作用及药物相互作用。我们报告一例30岁患有重度子痫前期和HELLP综合征的女性，在接受硫酸镁和尼卡地平治疗期间，在全身麻醉下接受剖宫产手术。她出现了长时间的深度神经肌肉阻滞，三小时后用新斯的明进行了拮抗。在治疗性高镁血症的情况下，必须减少非去极化肌松药的剂量，并延长给药间隔时间，并进行适当的神经肌肉监测。
相似文献
1
Prolonged neuromuscular block in a preeclamptic patient induced by magnesium sulfate.硫酸镁诱发的先兆子痫患者的长时间神经肌肉阻滞。
Pan Afr Med J. 2016 Sep 14;25:5. doi: 10.11604/pamj.2016.25.5.6616. eCollection 2016.
2
[Sugammadex and profound rocuronium neuromuscular blockade induced by magnesium sulphate].[舒更葡糖钠与硫酸镁诱导的深度罗库溴铵神经肌肉阻滞]
Ann Fr Anesth Reanim. 2013 May;32(5):378-9. doi: 10.1016/j.annfar.2013.03.008. Epub 2013 May 10.
3
A noninvasive method in the differential diagnosis of vecuronium-induced and magnesium-induced protracted neuromuscular block in a severely preeclamptic patient.一种用于鉴别重度子痫前期患者维库溴铵诱导和镁诱导的持续性神经肌肉阻滞的非侵入性方法。
J Clin Anesth. 1996 Aug;8(5):392-7. doi: 10.1016/0952-8180(96)00087-6.
4
[Prolonged neuromuscular blockade with vecuronium in patient with triple pregnancy treated with magnesium sulfate].
Masui. 1997 Feb;46(2):266-70.
5
[A case of prolongation of rocuronium neuromuscular blockade in a pregnant patient receiving magnesium].
Masui. 2014 Jul;63(7):817-9.
6
Neuromuscular blockade after therapy with magnesium sulfate and amlodipine.硫酸镁和氨氯地平治疗后的神经肌肉阻滞
Eur J Obstet Gynecol Reprod Biol. 2010 Apr;149(2):225. doi: 10.1016/j.ejogrb.2009.11.008. Epub 2009 Dec 16.
7
Survey of postoperative residual curarization, acute respiratory events and approach of anesthesiologists.术后残余肌松、急性呼吸事件及麻醉医生处理方法的调查
Braz J Anesthesiol. 2016 Jan-Feb;66(1):55-62. doi: 10.1016/j.bjane.2012.06.011. Epub 2014 Apr 4.
8
[Complications of association magnesium sulfate with nicardipine during preeclampsia: report of 2 cases].
Gynecol Obstet Fertil. 2012 Oct;40(10):614-6. doi: 10.1016/j.gyobfe.2012.07.003. Epub 2012 Sep 13.
9
[Hypocalcemic delirium due to magnesium sulphate therapy in a pregnant woman with pre-eclampsia].[硫酸镁治疗子痫前期孕妇导致的低钙血症性谵妄]
Ned Tijdschr Geneeskd. 2002 Aug 3;146(31):1453-6.
10
Hypermagnesaemia and anaesthetic management.高镁血症与麻醉管理
Can Anaesth Soc J. 1982 Jan;29(1):35-41. doi: 10.1007/BF03007946.
引用本文的文献
1
Do Case Reports and Case Series Generate Clinical Discoveries About Preeclampsia? A Systematic Review.病例报告和病例系列研究能否产生关于子痫前期的临床发现？一项系统综述。
Int J Womens Health. 2023 Mar 21;15:411-425. doi: 10.2147/IJWH.S397680. eCollection 2023.
2
Postoperative residual neuromuscular block in a woman with severe preeclampsia treated with magnesium sulfate and nicardipine: A case report and literature review.硫酸镁和尼卡地平治疗重度子痫前期女性患者术后残余神经肌肉阻滞：一例病例报告及文献综述
Front Surg. 2023 Feb 23;10:1093969. doi: 10.3389/fsurg.2023.1093969. eCollection 2023.
3
Magnesium: the underestimated ion.镁：被低估的离子。
Braz J Anesthesiol. 2021 Sep-Oct;71(5):477-479. doi: 10.1016/j.bjane.2021.08.001.
4
Prolonged neuromuscular blockade and insufficient reversal after sugammadex administration in cesarean section under general anesthesia: a case report.全身麻醉下剖宫产术中使用舒更葡糖钠后神经肌肉阻滞延长及逆转不足：一例病例报告
JA Clin Rep. 2019 Apr 11;5(1):28. doi: 10.1186/s40981-019-0248-8.
5
Factors that affect the onset of action of non-depolarizing neuromuscular blocking agents.影响非去极化神经肌肉阻滞剂起效的因素。
Korean J Anesthesiol. 2017 Oct;70(5):500-510. doi: 10.4097/kjae.2017.70.5.500. Epub 2017 Sep 28.
本文引用的文献
1
Efficacy of sugammadex for the reversal of moderate and deep rocuronium-induced neuromuscular block in patients pretreated with intravenous magnesium: a randomized controlled trial.舒更葡糖钠用于逆转静脉注射镁预处理患者中、深度罗库溴铵诱导的神经肌肉阻滞的疗效：一项随机对照试验。
Anesthesiology. 2014 Jul;121(1):59-67. doi: 10.1097/ALN.0000000000000204.
2
Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.围手术期系统镁以最小化术后疼痛：随机对照试验的荟萃分析。
Anesthesiology. 2013 Jul;119(1):178-90. doi: 10.1097/ALN.0b013e318297630d.
3
Magnesium and the obstetric anaesthetist.镁与产科麻醉师。
Int J Obstet Anesth. 2013 Jan;22(1):52-63. doi: 10.1016/j.ijoa.2012.10.003. Epub 2012 Nov 22.
4
Neuromuscular blockade after therapy with magnesium sulfate and amlodipine.硫酸镁和氨氯地平治疗后的神经肌肉阻滞
Eur J Obstet Gynecol Reprod Biol. 2010 Apr;149(2):225. doi: 10.1016/j.ejogrb.2009.11.008. Epub 2009 Dec 16.
5
Prolonged relaxant effects of vecuronium in patients with deliberate hypermagnesemia: time for caution in cesarean section.维库溴铵在故意高镁血症患者中的延长肌松作用：剖宫产需谨慎的时机
J Anesth. 2006;20(1):33-5. doi: 10.1007/s00540-005-0354-9.
6
Magnesium in obstetric anesthesia.
Int J Obstet Anesth. 1998 Apr;7(2):115-23. doi: 10.1016/s0959-289x(98)90008-5.
7
Do women with pre-eclampsia, and their babies, benefit from magnesium sulphate? The Magpie Trial: a randomised placebo-controlled trial.患有先兆子痫的女性及其婴儿能从硫酸镁中获益吗？喜鹊试验：一项随机安慰剂对照试验。
Lancet. 2002 Jun 1;359(9321):1877-90. doi: 10.1016/s0140-6736(02)08778-0.
8
Clinical pharmacology of neuromuscular blocking agents.神经肌肉阻滞剂的临床药理学。
Am J Health Syst Pharm. 1999 Jun 1;56(11 Suppl 1):S4-9. doi: 10.1093/ajhp/56.S4.
9
Antagonism of vecuronium-induced neuromuscular block in patients pretreated with magnesium sulphate: dose-effect relationship of neostigmine.
Br J Anaesth. 1999 Jan;82(1):61-5. doi: 10.1093/bja/82.1.61.
10
Administration of magnesium sulphate before rocuronium: effects on speed of onset and duration of neuromuscular block.在使用罗库溴铵之前给予硫酸镁：对起效速度和神经肌肉阻滞持续时间的影响。
Br J Anaesth. 1997 Jul;79(1):122-4. doi: 10.1093/bja/79.1.122.
Zotero 插件