Pedersen I R, Mordhorst C H, Glikmann G, von Magnus H
Institute of Medical Microbiology, University of Copenhagen, Denmark.
Vaccine. 1989 Aug;7(4):345-8. doi: 10.1016/0264-410x(89)90199-0.
Measles vaccination was performed in the arctic district of Scoresbysund, Greenland in 1968, which had never been exposed to natural measles. More than 90% of the total population was vaccinated and a 94-100% seroconversion was obtained. During a serological survey to examine the immunity status of the vaccinees, it was discovered that a temporary increase in measles antibodies took place in the majority of the population 2-4 years after the vaccination. This was not accompanied by clinically observed measles. Most likely, it was due to an inapparent measles infection in a population considered highly immune after vaccination.
1968年，在格陵兰斯科斯比松的北极地区进行了麻疹疫苗接种，该地区从未接触过自然麻疹。超过90%的总人口接种了疫苗，血清转化率达到94%-100%。在一项检查疫苗接种者免疫状态的血清学调查中发现，大多数人在接种疫苗2-4年后麻疹抗体出现暂时增加。这并未伴随临床上观察到的麻疹。最有可能的原因是，在被认为接种疫苗后具有高度免疫力的人群中发生了隐性麻疹感染。
