Beskow P, Söderlind O, Thafvelin B
Zentralbl Veterinarmed B. 1989 Sep;36(7):487-94. doi: 10.1111/j.1439-0450.1989.tb00634.x.
The present investigation comprised six integrated herds (100-150 sows each) and one specialized fattening herd. Serologic tests by ELISA were performed on blood samples from piglets and growing pigs during various rearing phases in order to determine the presence of Actinobacillus infection and to estimate the age of the animals at onset of the disease. Using this information, herd-specific vaccination programs were designed against Actinobacillus pleuropneumoniae serotype 2. The weaned piglets in the integrated herds were vaccinated twice before being moved to the fattening unit. In the specialized fattening herd, the pigs were vaccinated on arrival at the growing unit and just before transfer to the finishing unit. The frequencies of chronic pleuritis at slaughter demonstrated that a vaccination program adapted to the herd-specific problem, in combination with environmental improvements, reduces the prevalence of chronic pleuritis. On the other hand, only a moderate reduction of the prevalence of chronic pleuritis occurred as a result of vaccination if no environmental improvements were made. In two of the herds during the vaccination period, the number of feeding days and food consumption decreased, while growth per day increased. There was also an apparent correlation between higher serum titres and a decreased prevalence of pleuritis at slaughter in three of the herds.
本次调查包括六个综合猪场（每个猪场有100 - 150头母猪）和一个专门的育肥猪场。在仔猪和生长猪的不同饲养阶段，对其血液样本进行了ELISA血清学检测，以确定是否存在放线杆菌感染，并估计动物发病时的年龄。利用这些信息，针对2型胸膜肺炎放线杆菌设计了特定猪场的疫苗接种计划。综合猪场的断奶仔猪在转入育肥单元前接种两次疫苗。在专门的育肥猪场，猪只在到达生长单元时以及转入育肥单元前接种疫苗。屠宰时慢性胸膜炎的发生率表明，结合环境改善措施，针对特定猪场问题的疫苗接种计划可降低慢性胸膜炎的患病率。另一方面，如果不进行环境改善，仅通过疫苗接种，慢性胸膜炎的患病率仅会适度降低。在疫苗接种期间，其中两个猪场的采食天数和食物消耗量减少，而日生长量增加。在其中三个猪场中，血清滴度较高与屠宰时胸膜炎患病率降低之间也存在明显的相关性。
