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Regulation of muscle growth and regeneration by the immune system.

作者信息

Tidball James G

机构信息

Molecular, Cellular and Integrative Physiology Program, University of California, Los Angeles, California 90095-1606, USA.

出版信息

Nat Rev Immunol. 2017 Mar;17(3):165-178. doi: 10.1038/nri.2016.150. Epub 2017 Feb 6.


DOI:10.1038/nri.2016.150
PMID:28163303
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5452982/
Abstract

Diseases of muscle that are caused by pathological interactions between muscle and the immune system are devastating, but rare. However, muscle injuries that involve trauma and regeneration are fairly common, and inflammation is a clear feature of the regenerative process. Investigations of the inflammatory response to muscle injury have now revealed that the apparently nonspecific inflammatory response to trauma is actually a complex and coordinated interaction between muscle and the immune system that determines the success or failure of tissue regeneration.

摘要

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本文引用的文献

[1]
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Stem Cell Res. 2016-7

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Cell. 2016-6-16

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