Yoshida K, Ando M, Sakata T, Araki S
First Department of Internal Medicine, Kumamoto University Medical School, Japan.
Arch Environ Health. 1989 Sep-Oct;44(5):317-22. doi: 10.1080/00039896.1989.9935900.
To prevent summer-type hypersensitivity pneumonitis, the effect of eliminating Trichosporon cutaneum from patients' homes was investigated. To determine environmental factors associated with enhanced indoor mold growth, we compared 11 patients' homes in which T. cutaneum was isolated to 32 control homes by inspection and indoor mold survey. Statistically significantly higher isolates of T. cutaneum, total yeasts, and total fungi were associated with unsanitary rooms, and especially with damp places in the wood or tatami mats in patients' homes. Cleaning, disinfecting, and removing the colonizing locations of T. cutaneum were performed. No recurrence was observed in 6 well-cleaned homes, but recurrence was observed in all patients who resided in homes that were not cleaned or in homes where cleaning was not adequate, and where T. cutaneum was not eliminated. The efficacy of therapy by elimination of T. cutaneum was proven.
为预防夏季型过敏性肺炎，我们研究了从患者家中清除皮状丝孢酵母的效果。为确定与室内霉菌生长增强相关的环境因素，我们通过检查和室内霉菌调查，将11例分离出皮状丝孢酵母的患者家庭与32个对照家庭进行了比较。皮状丝孢酵母、总酵母菌和总真菌的分离株在统计学上显著高于不卫生的房间，尤其是患者家中木材或榻榻米垫子的潮湿部位。我们进行了清洁、消毒并清除了皮状丝孢酵母的定殖场所。6个清洁良好的家庭未观察到复发，但居住在未清洁或清洁不充分且未清除皮状丝孢酵母的家庭中的所有患者均出现了复发。清除皮状丝孢酵母的治疗效果得到了证实。
