Johansson Cecilia, Dahlqvist Erik, Andersson Jonas, Jansson Jan-Håkan, Johansson Lars
Department of Public Health and Clinical Medicine, Skellefteå Research Unit, Umeå University, Umeå, Västerbotten, Sweden.
Clin Epidemiol. 2017 Jan 24;9:53-62. doi: 10.2147/CLEP.S122916. eCollection 2017.
The aims of this study were to estimate the incidence of atrial fibrillation and atrial flutter (AF), to assess the presence of provoking factors and risk factors for stroke and systemic embolism, and to determine the type of AF in patients with first-diagnosed AF.
This cohort study was performed in northern Sweden between January 1, 2011 and December 31, 2012. Diagnosis registries were searched for the International Classification of Diseases-10 code for AF (I48) to identify cases of incident AF. All AF diagnoses were electrocardiogram-verified. Data pertaining to provoking factors, type of AF and presence of risk factors for stroke and systemic embolism according to the CHADS-VASc score were obtained from medical records.
The incidence of AF in the entire population was 4.0 per 1,000 person-years. The incidence was 27.5 per 1,000 person-years in patients aged ≥80 years. A total of 21% of all patients had a provoking factor in association with the first-diagnosed episode of AF. The CHADS-VASc score was 2 or higher in 81% of the patients. Permanent AF was the most common type of AF (29%).
There was a considerable increase in the incidence of AF with age, and a provoking factor was found in one-fifth. The most common type of AF was permanent AF. Four in five patients had a CHADS-VASc score of 2 or more.
本研究旨在估计心房颤动和心房扑动（房颤）的发病率，评估诱发因素以及中风和全身性栓塞的危险因素的存在情况，并确定首次诊断为房颤的患者的房颤类型。
这项队列研究于2011年1月1日至2012年12月31日在瑞典北部进行。通过搜索诊断登记处，查找房颤的国际疾病分类-10代码（I48）以识别新发房颤病例。所有房颤诊断均经心电图证实。从病历中获取与诱发因素、房颤类型以及根据CHADS-VASc评分得出的中风和全身性栓塞危险因素的存在情况相关的数据。
整个人群中房颤的发病率为每1000人年4.0例。80岁及以上患者的发病率为每1000人年27.5例。所有患者中共有21%在首次诊断为房颤的发作时有诱发因素。81%的患者CHADS-VASc评分为2分或更高。永久性房颤是最常见的房颤类型（29%）。
房颤的发病率随年龄显著增加，五分之一的患者存在诱发因素。最常见的房颤类型是永久性房颤。五分之四的患者CHADS-VASc评分为2分或更高。
