Alarcón F, Escalante L, Dueñas G, Montalvo M, Román M
Department of Neurology, Eugenio Espejo Hospital, Quito, Ecuador.
Arch Neurol. 1989 Nov;46(11):1231-6. doi: 10.1001/archneur.1989.00520470099034.
Eighteen patients with nonenhancing parenchymal brain cysts were treated with albendazole; 9 patients were treated for 3 days and 9 patients for 1 month at daily doses of 15 mg/kg of body weight. Three months after starting therapy, results showed that in both groups the treatment was highly effective. Control studies carried out in the same group before the trial did not show any significant improvement. Five patients were controls and were treated only with symptomatic drugs. The total diameter of the lesions was reduced from 220.1 mm to 52.1 mm, which signifies a reduction of 76.3% in patients treated for a period of 3 days, and from 278.5 mm to 82.1 mm, which is 70.5%, in patients treated for 30 days. We conclude that albendazole administered according to the 3-day therapeutic scheme proposed above is as highly effective for the treatment of parenchymal brain cysticercosis as the 30-day scheme.
18例脑实质非强化性囊肿患者接受了阿苯达唑治疗；9例患者接受了3天治疗，9例患者接受了1个月治疗，每日剂量为15mg/kg体重。开始治疗3个月后，结果显示两组治疗均非常有效。试验前在同一组中进行的对照研究未显示出任何显著改善。5例患者为对照组，仅接受对症药物治疗。病变的总直径从220.1mm减小到52.1mm，这意味着接受3天治疗的患者减少了76.3%，而接受30天治疗的患者从278.5mm减小到82.1mm，减少了70.5%。我们得出结论，按照上述3天治疗方案给予阿苯达唑治疗脑实质囊尾蚴病与30天方案一样有效。
