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口服阿苯达唑治疗眼外囊尾蚴病

Oral albendazole in the management of extraocular cysticercosis.

作者信息

Sihota R, Honavar S G

机构信息

Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi.

出版信息

Br J Ophthalmol. 1994 Aug;78(8):621-3. doi: 10.1136/bjo.78.8.621.

DOI:10.1136/bjo.78.8.621
PMID:7918290
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC504887/
Abstract

Surgical removal of extraocular cysticerci is fraught with complications. The effect of oral albendazole in such cases has been evaluated in a randomised, controlled, clinical trial. Of 24 ultrasonographically diagnosed, and ELISA positive cases of extraocular cysticerci, 12 received oral albendazole 15 mg/kg once daily for 1 month, while the 12 controls received a placebo. Marked clinical improvement was seen in all the cases in the treatment group at 4 weeks, with collapse of the cyst at 6 weeks (75%), and complete disappearance at 3 months (100%). No clinical or ultrasonographical change was noted in the control group. A trial of medical management with oral albendazole merits consideration in cases of extraocular cysticerci.

摘要

手术切除眼外囊尾蚴充满并发症。在一项随机对照临床试验中评估了口服阿苯达唑在此类病例中的效果。在24例经超声诊断且ELISA呈阳性的眼外囊尾蚴病例中，12例接受口服阿苯达唑，剂量为15mg/kg，每日1次，共1个月，而12例对照组接受安慰剂。治疗组所有病例在4周时临床有明显改善，6周时囊肿塌陷（75%），3个月时完全消失（100%）。对照组未观察到临床或超声变化。对于眼外囊尾蚴病例，值得考虑采用口服阿苯达唑进行药物治疗试验。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0a5/504887/8513efdc488e/brjopthal00032-0028-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0a5/504887/e48a64094024/brjopthal00032-0028-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0a5/504887/8513efdc488e/brjopthal00032-0028-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0a5/504887/e48a64094024/brjopthal00032-0028-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0a5/504887/8513efdc488e/brjopthal00032-0028-b.jpg

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本文引用的文献

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OCULAR CYSTICERCOSIS.眼囊尾蚴病
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