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皮肤搔抓障碍的替代疗法:简要更新

Alternative Therapies for Excoriation (Skin Picking) Disorder: A Brief Update.

作者信息

Torales Julio, Barrios Iván, Villalba Jorge

出版信息

Adv Mind Body Med. 2017;31(1):10-13.

Abstract

Context • Excoriation (skin picking) disorder is characterized by the need or urge to pick, scratch, pinch, touch, rub, scrub, squeeze, bite, or dig the skin, and it can be a perplexing condition for the inexperienced physician. Treatments include pharmacotherapy, psychotherapy, and alternative therapies. Alternative therapies for excoriation disorder and other body-focused repetitive behaviors include yoga, aerobic exercise, acupuncture, biofeedback, hypnosis, and inositol and N-acetylcysteine, among others. Objective • This review article intended to review the current literature on the alternative therapies to provide a brief update on their benefits for the treatment of excoriation disorder for use in conjunction with psychotherapy and pharmacotherapy in the management of a challenging group of patients. Design • This review (focusing on literature published in the last 15 y, selected from a search of PubMed) critically considers the evidence for the use of alternative therapies in the treatment of excoriation disorder. Setting • This review was conducted at the National University of Asunción (San Lorenzo, Paraguay). Results • Results for yoga were as follows: This technique may influence the structure and functioning of the areas of emotional processing involved in the pathophysiology of excoriation disorder and other body-focused repetitive behaviors, such as trichotillomania. Although still limited, the current research team's use of yoga as a treatment has given useful results. Results for aerobic exercise were as follows: People suffering from excoriation disorder and other-body focused repetitive behaviors generally have a worsening of their behaviors in times of negative mood and anxiety. As exercise has qualities that allow individuals to improve their mood and reduce their anxiety, it is likely that it also can help reduce behaviors like hair pulling or scratching, and it should be considered to be an adjunctive therapy. Results for acupuncture were as follows: The mechanism of action of acupuncture increases serotonergic activity and releases endorphins in the hypothalamus and limbic region, which could be beneficial in patients with trichotillomania and excoriation disorder. Results for biofeedback were as follows: Several case reports have suggested the value of biofeedback in reducing tics, which bear some psychophysiological similarities to body-focused repetitive behaviors, such as trichotillomania and excoriation disorder. Results for hypnosis were as follows: When used as a channel for other types of interventions, such as psychotherapy, hypnosis can help counteract the stress that triggers the picking behaviors in some patients. Results for inositol and N-acetylcysteine were as follows: Although more research is needed, these are promising drugs that may be helpful in reducing the picking behavior. Conclusions • The review indicates that yoga, aerobic exercise, acupuncture, biofeedback, hypnosis, and inositol and N-acetylcysteine all show promise in the treatment of excoriation disorder and other body-focused repetitive behaviors, such as trichotillomania. In the current research team's experience, mainly yoga and aerobic exercise have been shown useful in combination with psychotherapy and pharmacotherapy. Obtaining solid evidence about the long-term beneficial effects of these alternative therapies for the treatment of excoriation disorder requires more investigation.

摘要

背景 • 皮肤搔抓障碍的特征是有搔抓、刮擦、捏、触摸、摩擦、擦洗、挤压、咬或抠皮肤的需求或冲动,对于经验不足的医生来说,这可能是一种令人困惑的病症。治疗方法包括药物治疗、心理治疗和替代疗法。用于皮肤搔抓障碍和其他专注于身体的重复行为的替代疗法包括瑜伽、有氧运动、针灸、生物反馈、催眠以及肌醇和N-乙酰半胱氨酸等。

目的 • 这篇综述文章旨在回顾有关替代疗法的当前文献,简要介绍其在治疗皮肤搔抓障碍方面的益处,以便在治疗具有挑战性的患者群体时与心理治疗和药物治疗联合使用。

设计 • 本综述(重点关注过去15年发表的文献,通过检索PubMed选取)批判性地考虑了替代疗法用于治疗皮肤搔抓障碍的证据。

地点 • 本综述在亚松森国立大学(巴拉圭圣洛伦索)进行。

结果 • 瑜伽的结果如下:该技术可能会影响皮肤搔抓障碍和其他专注于身体的重复行为(如拔毛癖)病理生理学中涉及情绪处理区域的结构和功能。尽管目前的研究仍然有限,但当前研究团队将瑜伽用作治疗方法已取得了有益的结果。

有氧运动的结果如下

患有皮肤搔抓障碍和其他专注于身体的重复行为的人在情绪消极和焦虑时,其行为通常会恶化。由于运动具有改善情绪和减轻焦虑的特性,因此它也可能有助于减少拔毛或搔抓等行为,应被视为一种辅助疗法。

针灸的结果如下

针灸的作用机制可增加血清素能活性,并在下丘脑和边缘区域释放内啡肽,这可能对拔毛癖和皮肤搔抓障碍患者有益。

生物反馈的结果如下

几例病例报告表明生物反馈在减少抽动方面具有价值,抽动与专注于身体的重复行为(如拔毛癖和皮肤搔抓障碍)在心理生理上有一些相似之处。

催眠的结果如下

当用作其他类型干预(如心理治疗)的渠道时,催眠可以帮助抵消一些患者中引发搔抓行为的压力。

肌醇和N-乙酰半胱氨酸的结果如下:尽管需要更多研究,但这些都是有前景的药物,可能有助于减少搔抓行为。

结论 • 该综述表明,瑜伽、有氧运动、针灸、生物反馈、催眠以及肌醇和N-乙酰半胱氨酸在治疗皮肤搔抓障碍和其他专注于身体的重复行为(如拔毛癖)方面均显示出前景。根据当前研究团队的经验,主要是瑜伽和有氧运动已被证明与心理治疗和药物治疗联合使用时有用。要获得关于这些替代疗法对治疗皮肤搔抓障碍长期有益效果的确凿证据,还需要更多研究。

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