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皮肤搔抓障碍:治疗选择的系统评价

Excoriation (skin-picking) disorder: a systematic review of treatment options.

作者信息

Lochner Christine, Roos Annerine, Stein Dan J

机构信息

SU/UCT MRC Unit on Risk and Resilience in Mental Disorders, Department of Psychiatry, Stellenbosch University, South Africa.

SU/UCT MRC Unit on Risk and Resilience in Mental Disorders, Department of Psychiatry and Mental Health, University of Cape Town, South Africa.

出版信息

Neuropsychiatr Dis Treat. 2017 Jul 14;13:1867-1872. doi: 10.2147/NDT.S121138. eCollection 2017.

Abstract

Although pathological skin-picking has been documented in the medical literature since the 19th century, it has only recently been included as a distinct entity in psychiatric classification systems. In the , 5th Edition and the proposed International Classification of Diseases, Eleventh Revision, excoriation (skin-picking) disorder (ED), also known as neurotic excoriation, psychogenic excoriation, or dermatillomania), is described as recurrent picking of skin, leading to skin lesions and significant distress or functional impairment. ED is listed as one of the obsessive-compulsive and related disorders, given its overlap with conditions such as trichotillomania (hair-pulling disorder). Arguably, its inclusion and delineation in the diagnostic nomenclature will lead to increased awareness of the condition, more research, and ultimately in treatment advances. This systematic review aims to provide readers with an up-to-date view of current treatment options for ED. A MEDLINE search of the ED treatment literature was conducted to collate relevant articles published between 1996 and 2017. The findings indicate that a number of randomized controlled trails on ED have now been published, and that current management options include behavioral therapy (habit reversal or acceptance-enhanced behavior therapy), and medication (selective serotonin reuptake inhibitors or -acetyl cysteine).

摘要

尽管自19世纪起医学文献中就有关于病理性皮肤搔抓的记载,但直到最近它才被纳入精神疾病分类系统成为一个独立的病种。在《精神疾病诊断与统计手册》第5版和提议中的《国际疾病分类》第11版中,皮肤搔抓障碍(ED),也被称为神经性皮肤搔抓、心因性皮肤搔抓或人工皮炎,被描述为反复搔抓皮肤,导致皮肤损伤并引起显著痛苦或功能损害。鉴于ED与拔毛癖(拔毛发障碍)等疾病存在重叠,它被列为强迫症及相关障碍之一。可以说,将其纳入诊断术语并进行明确界定将提高对该疾病的认识,促进更多研究,最终推动治疗进展。本系统综述旨在为读者提供关于ED当前治疗选择的最新观点。通过对MEDLINE数据库中ED治疗文献进行检索,整理出1996年至2017年期间发表的相关文章。研究结果表明,目前已发表了一些关于ED的随机对照试验,当前的治疗选择包括行为疗法(习惯逆转或接受增强行为疗法)和药物治疗(选择性5-羟色胺再摄取抑制剂或N-乙酰半胱氨酸)。

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