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腭前成形术对单纯打鼾及阻塞性睡眠呼吸暂停综合征患者上气道参数的CT评估

Evaluation of effects of anterior palatoplasty operation on upper airway parameters in computed tomography in patients with pure snoring and obstructive sleep apnea syndrome.

作者信息

Selcuk Adin, Ozer Tulay, Esen Erkan, Ozdogan Fatih, Ozel Halil Erdem, Yuce Turgut, Caliskan Sebla, Dasli Sinem, Bilal Nagihan, Genc Gulden, Genc Selahattin

机构信息

Derince Education and Research Hospital ENT Clinic, 41100, Derince, Kocaeli, Turkey.

Derince Education and Research Hospital Radiology Clinic, Derince, Kocaeli, Turkey.

出版信息

Eur Arch Otorhinolaryngol. 2017 May;274(5):2183-2188. doi: 10.1007/s00405-016-4448-9. Epub 2017 Feb 9.

DOI:10.1007/s00405-016-4448-9
PMID:28185010
Abstract

AIM

To investigate changes in upper airway volume parameters measured by computerized tomography scans in patients with surgically treated by anterior palatoplasty of whom having pure snoring and mild-moderate obstructive sleep apnea.

METHOD

A prospective study on consecutively anterior palatoplasty performed pure snoring and obstructive sleep apnea patients. Computerized tomography scans were obtained preoperatively and following anterior palatoplasty procedure to measure changes in upper airway volume. Patients underwent diagnostic drug induced sleep endoscopy to assess the site of obstruction. Preoperative and postoperative measurements were compared using student's t test and Chi-square test.

RESULTS

Twenty-two patients (16 men and 6 women, age 48.22 ± 9.23, body mass index 25.85 ± 2.57) completed the trial. Anterior palatoplasty was associated with an increase in total upper airway volume from 4.81 ± 1.73 cm before treatment to 6.57 ± 2.03 cm after treatment (p < 0.005). Change in soft palate thickness did not vary significantly (p < 0.039). The mean soft palate length has changed from 4.13 ± 0.41 to 3.93 ± 0.51 cm (p < 0.001). The preoperative and postoperative measurements of cross-sectional areas and volumes all showed significant difference except velopharynx minimal lateral airway dimension. The operational procedure increased the total upper airway volume much more in men than in women (p < 0.05).

CONCLUSION

Results of this study indicate that anterior palatoplasty operation appears to produce significant increase in upper airway volume and cross sectional area. It does not seem to have an effect on lateral airway dimension. Computerized tomography is a quick and noninvasive imaging technique that allows for quantitative assessment of the velopharyngeal patency changes.

摘要

目的

研究经前腭成形术治疗的单纯打鼾及轻中度阻塞性睡眠呼吸暂停患者,通过计算机断层扫描测量的上气道容积参数的变化。

方法

对连续接受前腭成形术的单纯打鼾和阻塞性睡眠呼吸暂停患者进行前瞻性研究。术前及前腭成形术后行计算机断层扫描以测量上气道容积的变化。患者接受诊断性药物诱导睡眠内镜检查以评估阻塞部位。术前和术后测量结果采用学生t检验和卡方检验进行比较。

结果

22例患者(16例男性,6例女性,年龄48.22±9.23,体重指数25.85±2.57)完成试验。前腭成形术使上气道总体积从治疗前的4.81±1.73cm增加至治疗后的6.57±2.03cm(p<0.005)。软腭厚度变化无显著差异(p<0.039)。软腭平均长度从4.13±0.41cm变为3.93±0.51cm(p<0.001)。除腭咽最小侧气道尺寸外,术前和术后的横截面积和容积测量均显示出显著差异。手术操作使男性上气道总体积增加幅度远大于女性(p<0.05)。

结论

本研究结果表明,前腭成形术似乎能显著增加上气道容积和横截面积。它似乎对侧气道尺寸没有影响。计算机断层扫描是一种快速且无创的成像技术,可对腭咽通畅性变化进行定量评估。

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