Li Hseuh-Yu, Li Kasey K, Chen Ning-Hung, Wang Chao-Jan, Liao Yu-Fang, Wang Pa-Chun
Department of Otolaryngology, Chang Gung Memorial Hospital, Taipei, Taiwan.
Am J Otolaryngol. 2005 Jan-Feb;26(1):7-11. doi: 10.1016/j.amjoto.2004.06.006.
Using both sleep physiological parameters and image data to evaluate the efficacy of extended uvulopalatal flap (EUPF) surgery in the treatment of obstructive sleep apnea (OSA).
Fifty patients with OSA underwent EUPF that consisted of bilateral tonsillectomy, dissection and removal of the submucosal adipose tissue of the soft palate and supratonsillar areas, and imbrications and repositioning of the denuded uvulopalatal flap. Polysomnography (PSG) and 3-dimensional computed tomography (3-D CT) data were obtained at baseline and 6 months postoperatively. Good response to surgery was defined as a reduction of the respiratory disturbance index (RDI) to less than 20 events/h and a greater than 50% reduction of the baseline RDI.
Forty-two patients (84%) achieved good results. The RDI and minimal O2 saturation improved significantly (P<.0001) after EUPF. The postoperative 3-D CT evaluation showed a significant increase in the retropalatal space (P<.0001). The preoperative lateral diameter of retropalatal space was predictive of the change of RDI (R2=0.15, P=.05). The effect of increased retropalatal space (r=0.59, P=.0415) was significant in patients with baseline RDI ranged from 31 to 60 events/h.
With special emphasis on the removal of palatal fat, EUPF appeared to be effective in the reduction of sleep apnea in selected patients. 3-D CT proved that this technique was effective in widening the upper airway by relieving the retropalatal obstruction.
利用睡眠生理参数和图像数据评估延长悬雍垂腭咽成形术(EUPF)治疗阻塞性睡眠呼吸暂停(OSA)的疗效。
50例OSA患者接受了EUPF手术,包括双侧扁桃体切除术、软腭和扁桃体上区黏膜下脂肪组织的剥离与切除,以及裸露的悬雍垂腭瓣的重叠和重新定位。在基线和术后6个月获取多导睡眠图(PSG)和三维计算机断层扫描(3-D CT)数据。手术良好反应定义为呼吸紊乱指数(RDI)降至低于20次/小时且较基线RDI降低超过50%。
42例患者(84%)取得良好效果。EUPF术后RDI和最低氧饱和度显著改善(P<0.0001)。术后3-D CT评估显示腭后间隙显著增加(P<0.0001)。术前腭后间隙的横向直径可预测RDI的变化(R2=0.15,P=0.05)。在基线RDI为31至60次/小时的患者中,腭后间隙增加的效果显著(r=0.59,P=0.0415)。
特别强调腭部脂肪的去除,EUPF似乎对特定患者减少睡眠呼吸暂停有效。3-D CT证明该技术通过缓解腭后阻塞有效扩大上气道。