Kheniser Karim G, Kashyap Sangeeta R, Schauer Philip R, Lam Eddie T C, Kullman Emily S
Department of Endocrinology and Metabolism, Cleveland Clinic, 9500 Euclid Avenue F20, Cleveland, OH, 44195, USA.
Bariatric and Metabolic Institute, Metabolic Translational Research Center, Endocrine and Metabolism Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.
Obes Surg. 2017 May;27(5):1381-1386. doi: 10.1007/s11695-017-2573-1.
Although bariatric surgery fosters heightened excess weight loss values, nutritional deficiencies are prominent; one of the most common being iron deficiency anemia. The purpose is to elucidate the frequency of anemia in Roux-en-Y gastric bypass and sleeve gastrectomy subjects.
A retrospective analysis was conducted, in subjects (N = 100) diagnosed with type II diabetes who were randomized into sleeve gastrectomy or Roux-en-Y gastric bypass and intensive medical therapy.
Anemia was more common in female subjects who underwent sleeve gastrectomy-roughly half developed microcytosis at 24 months and thereafter.
The etiology of anemia appears to be iron-related and precipitated by the female sex. Scant iron supplementation is likely causative. However, anemia of chronic inflammation cannot be discounted as being somewhat causal. Subsequently, the aggregate may have had a synergistic influence.
尽管减肥手术能带来更高的体重减轻值，但营养缺乏问题较为突出；其中最常见的一种是缺铁性贫血。目的是阐明接受Roux-en-Y胃旁路手术和袖状胃切除术的患者中贫血的发生率。
对100名被诊断为II型糖尿病的患者进行回顾性分析，这些患者被随机分为接受袖状胃切除术或Roux-en-Y胃旁路手术及强化药物治疗。
接受袖状胃切除术的女性患者中贫血更为常见——大约一半患者在24个月及之后出现小红细胞症。
贫血的病因似乎与铁有关，且女性更容易引发。铁补充不足可能是原因所在。然而，慢性炎症性贫血也不能排除有一定的因果关系。随后，两者可能产生了协同作用。
