CNRS, Institut de Chimie des Substances Naturelles , 91198 Gif-sur-Yvette, France.
CNRS, UMR EcoFoG, AgroParisTech, Cirad, INRA, Université des Antilles, Université de Guyane , 97300 Cayenne, France.
J Nat Prod. 2017 Feb 24;80(2):384-390. doi: 10.1021/acs.jnatprod.6b00850. Epub 2017 Feb 10.
Four new sesquiterpene alkaloids (1-4) with a β-dihydroagrofuran skeleton and a new triterpenoid (5) were isolated from an ethyl acetate extract of Maytenus oblongata stems. Their structures were elucidated using 1D and 2D NMR spectroscopy as well as MS and ECD experiments. The M. oblongata stem EtOAc extract and the pure compounds isolated were tested for larvicidal activity against Aedes aegypti under laboratory conditions, and compounds 2 and 3 were found to be active.
从卷柏茎的乙酸乙酯提取物中分离得到了四个具有β-二氢沉香呋喃骨架的新倍半萜生物碱（1-4）和一个新的三萜（5）。通过 1D 和 2D NMR 光谱以及 MS 和 ECD 实验阐明了它们的结构。在实验室条件下，对埃及伊蚊进行了幼虫致死活性测试，结果表明，卷柏茎乙酸乙酯提取物和分离得到的纯化合物 2 和 3 具有活性。
