Sinaei Farnaz, Zendehdel Kazem, Adili Mahsa, Ardestani Atefeh, Montazeri Ali, Mohagheghi Mohammad Ali
Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran. AND Students' Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Cancer Biology Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran.
Acta Med Iran. 2017 Jan;55(1):35-41.
Breast reconstruction (BR) surgery is not common for the treatment of breast cancer in low- and middle-income countries, including Iran. We evaluated the quality of life (QoL) in Iranian breast cancer patients who underwent BR at the Cancer Institute of Iran. We compared patients who had BR with breast cancer patients who had a radical mastectomy as the control group, matched for age, and time since surgery. We interviewed the cases and controls and collected data about QoL using EORTC-Q30 and EORTC-Q23 questionnaires. We also obtained personal and clinical data for the patients and controls. We compared 61 BR and 45 radical mastectomy patients. The BR patients had a higher level of education (73.8%) than the mastectomy patients (27.3%). In addition, the BR patients had a higher employment rate (58%) than the mastectomy patients (4.4%). QoL was significantly better among BR patients compared to the control group (P<0.05). In the multivariable analyses, the BR patients had significantly lower scores of pain, fatigue, and diarrhoea than the controls. Breast cancer patients who underwent BR surgery had a higher quality of life scores in some domains compared to the radical mastectomy. Socioeconomic factors and awareness of the patients about BR was crucial for choosing BR among Iranian patients.
在包括伊朗在内的低收入和中等收入国家，乳房重建（BR）手术在乳腺癌治疗中并不常见。我们评估了在伊朗癌症研究所接受BR手术的乳腺癌患者的生活质量（QoL）。我们将接受BR手术的患者与接受根治性乳房切除术的乳腺癌患者作为对照组进行比较，对照组在年龄和手术时间上进行了匹配。我们对病例组和对照组进行了访谈，并使用欧洲癌症研究与治疗组织生活质量核心问卷（EORTC-Q30）和欧洲癌症研究与治疗组织乳腺癌特异性问卷（EORTC-Q23）收集了有关生活质量的数据。我们还获取了患者和对照组的个人及临床数据。我们比较了61例接受BR手术的患者和45例接受根治性乳房切除术的患者。接受BR手术的患者受教育程度（73.8%）高于接受乳房切除术的患者（27.3%）。此外，接受BR手术的患者就业率（58%）高于接受乳房切除术的患者（4.4%）。与对照组相比，BR患者的生活质量明显更好（P<0.05）。在多变量分析中，BR患者的疼痛、疲劳和腹泻评分明显低于对照组。与根治性乳房切除术相比，接受BR手术的乳腺癌患者在某些领域的生活质量得分更高。社会经济因素以及患者对BR的认知对于伊朗患者选择BR至关重要。
