托斯卡纳制革行业工人的癌症死亡率。
Cancer mortality among workers in the Tuscan tanning industry.
作者信息
Costantini A S, Paci E, Miligi L, Buiatti E, Martelli C, Lenzi S
机构信息
Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy.
出版信息
Br J Ind Med. 1989 Jun;46(6):384-8. doi: 10.1136/oem.46.6.384.
The mortality of 2926 male workers at the tanneries in the "leather area" of Tuscany was examined from 1950 to 1983 comparing it with the national mortality. Cancer mortality was of particular concern because of the many chemicals known to be definite or suspected carcinogens used in the tanning cycle, in particular chromate pigments, benzidine based dyes, formaldehyde, and organic solvents. There was no excess of deaths for cancers of all sites but slight increases in deaths from cancer of the lung (SMR = 131, CI 95% = 88-182), bladder (SMR = 150, CI 95% = 48-349), kidney (SMR = 323, CI 95% = 86-827), pancreas (SMR = 146, CI 95% = 39-373), and leukaemias (SMR = 164, CI 95% = 53-382) occurred. Two cases of soft tissue sarcomas were observed versus 0.09 expected (SMR = 2178, CI 95% = 250-8023).
对1950年至1983年期间托斯卡纳“皮革区”制革厂的2926名男性工人的死亡率进行了调查，并与全国死亡率进行了比较。由于在鞣制过程中使用了许多已知的确定性或疑似致癌物，尤其是铬酸盐颜料、联苯胺基染料、甲醛和有机溶剂，癌症死亡率尤其令人关注。所有部位癌症的死亡人数并未超标，但肺癌（标准化死亡比=131，95%置信区间=88-182）、膀胱癌（标准化死亡比=150，95%置信区间=48-349）、肾癌（标准化死亡比=323，95%置信区间=86-827）、胰腺癌（标准化死亡比=146，95%置信区间=39-373）和白血病（标准化死亡比=164，95%置信区间=53-382）的死亡人数出现了轻微增加。观察到2例软组织肉瘤病例，而预期为0.09例（标准化死亡比=2178，95%置信区间=250-8023）。
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