多系统萎缩中膀胱和运动症状的起病：根据表型的差异
Onset of bladder and motor symptoms in multiple system atrophy: differences according to phenotype.
作者信息
Zheng Jinhua, Yang Xinglong, Chen Yalan, Zhao Quanzhen, Tian Sijia, Huang Hongyan, Xu Yanming
机构信息
Department of Neurology, West China Hospital, Sichuan University, 37 Guo Xue Xiang, Chengdu, 610041, Sichuan, People's Republic of China.
出版信息
Clin Auton Res. 2017 Apr;27(2):103-106. doi: 10.1007/s10286-017-0405-y. Epub 2017 Feb 11.
PURPOSE
To compare the order of presentation of bladder and motor symptoms between multiple system atrophy phenotypes.
METHODS
Medical records were retrospectively reviewed in 144 patients.
RESULTS
Bladder symptoms occurred either before or within 12 months after onset of motor symptoms in significantly more patients with the cerebellar phenotype than the parkinsonian phenotype (80 vs. 53%, p = 0.003); similar results were observed for urinary incontinence (79 vs. 45%, p = 0.001).
CONCLUSIONS
Urinary dysfunction is more likely to appear either before or shortly after motor symptoms in the cerebellar phenotype than in the parkinsonian phenotype.
目的
比较多系统萎缩不同表型中膀胱症状和运动症状出现的先后顺序。
方法
对144例患者的病历进行回顾性分析。
结果
与帕金森型表型患者相比，小脑型表型患者中膀胱症状在运动症状出现之前或之后12个月内出现的比例显著更高（80%对53%，p = 0.003）；尿失禁情况也有类似结果（79%对45%，p = 0.001）。
结论
与帕金森型表型相比，小脑型表型中排尿功能障碍更可能在运动症状之前或之后不久出现。
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