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骨膜下微创美学牙槽嵴增高术(SMART):颌骨骨重建的新标准。

Subperiosteal Minimally Invasive Aesthetic Ridge Augmentation Technique (SMART): A New Standard for Bone Reconstruction of the Jaws.

作者信息

Lee Ernesto A

出版信息

Int J Periodontics Restorative Dent. 2017 Mar/Apr;37(2):165-173. doi: 10.11607/prd.3171.

Abstract

Traditional guided bone regeneration techniques include flap mobilization and placement of a bone graft, often with the use of space-maintaining devices and cell-occlusive membranes. This approach is associated with frequent complications that negatively affect the outcome of the augmentation and the peri-implant soft tissue esthetics. Although current tunneling techniques have focused on periodontal soft tissue applications, earlier publications described their use for horizontal augmentation of mandibular posterior edentulous ridges in full-denture patients. More recently, the use of recombinant human platelet-derived growth factor (rhPDGF-BB) was tested with different bone matrices to treat maxillary anterior edentulous spans. The present case series reports the use of a subperiosteal minimally invasive aesthetic ridge augmentation technique (SMART) to treat 60 single and multiple edentulous, dentate, and implant sites on 21 patients and five treatment categories with a follow-up period ranging from 4 to 30 months. The technique includes the use of a laparoscopic approach to deliver a growth factor/xenograft combination into a subperiosteal pouch. No flap elevation, cell-occlusive membranes, space-maintaining devices, or decortication procedures were used. The results from this case series demonstrated predictable and consistent bone regeneration. The average gain in ridge width for all treatment categories was 5.11 mm (SD 0.76 mm), which compares favorably with previously published reports. Morbidity and complication rates were consistently reduced as well. Human histology results show xenograft particles surrounded by newly formed bone. The role of the periosteum as a source of pluripotent cells in growth factor–mediated bone regeneration is discussed.

摘要

传统的引导骨再生技术包括掀起皮瓣并植入骨移植材料,通常还会使用空间维持装置和细胞封闭膜。这种方法常常伴随着一些并发症,会对种植体周围软组织美学效果及种植体植入后的骨增量结果产生负面影响。尽管目前的隧道技术主要应用于牙周软组织,但早期文献描述了其在下颌后牙区无牙颌患者水平骨增量中的应用。最近,重组人血小板衍生生长因子(rhPDGF - BB)与不同骨基质联合使用,用于治疗上颌前牙区无牙间隙。本病例系列报道了采用骨膜下微创美学牙槽嵴增量技术(SMART)对21例患者的60个单颗及多颗牙缺失、有牙及种植位点进行治疗,并分为五个治疗类别,随访期为4至30个月。该技术包括采用腹腔镜方法将生长因子/异种移植物组合植入骨膜下袋。未进行皮瓣掀起、使用细胞封闭膜、空间维持装置或去皮质操作。该病例系列结果显示骨再生具有可预测性且效果一致。所有治疗类别的牙槽嵴宽度平均增加5.11 mm(标准差0.76 mm),与先前发表的报告相比效果良好。发病率和并发症发生率也持续降低。人体组织学结果显示异种移植颗粒被新形成的骨组织包围。本文还讨论了骨膜作为生长因子介导的骨再生中多能细胞来源的作用。

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