Langston C, Cook A, Eatroff A, Mitelberg E, Chalhoub S
The Ohio State University College of Veterinary Medicine, Columbus, OH.
Veterinary Referral and Emergency Group, Brooklyn, NY.
J Vet Intern Med. 2017 Mar;31(2):402-409. doi: 10.1111/jvim.14658. Epub 2017 Feb 15.
Multiple factors exist that contribute to anemia in dogs and cats receiving hemodialysis, can necessitate transfusion.
To describe blood product usage in dogs and cats with acute and chronic kidney disease that were treated with intermittent hemodialysis to determine risk factors associated with the requirement for blood product transfusion.
83 cats and 147 dogs undergoing renal replacement therapy at the Animal Medical Center for acute or chronic kidney disease.
Retrospective medical record review of all dogs and cats receiving renal replacement therapy for kidney disease, from June 1997 through September 2012.
Blood products (whole blood, packed RBCs, or stromal-free hemoglobin) were administered to 87% of cats and 32% of dogs. The number of dialysis treatments was associated with the requirement for transfusion in cats (adjusted OR 2.21, 95% CI 1.13, 4.32), but not in dogs (adjusted OR 0.98, 95% CI 0.95, 1.03). Administration of a blood product was associated with a higher likelihood of death in dogs (OR 3.198, 95% CI 1.352, 7.565; P = .0098), but not in cats (OR 1.527, 95% CI 0.5404, 4.317, P = .2).
Veterinary hospitals with a hemodialysis unit should have reliable and rapid access to safe blood products in order to meet the needs of dogs and cats receiving dialysis.
接受血液透析的犬猫出现贫血的因素有多种，可能需要输血。
描述接受间歇性血液透析治疗的急慢性肾病犬猫的血液制品使用情况，以确定与血液制品输血需求相关的危险因素。
83只猫和147只犬在动物医疗中心接受急性或慢性肾病的肾脏替代治疗。
回顾性查阅1997年6月至2012年9月期间所有接受肾病肾脏替代治疗的犬猫的病历。
87%的猫和32%的犬接受了血液制品（全血、红细胞悬液或无基质血红蛋白）。透析治疗次数与猫的输血需求相关（调整后OR 2.21，95%CI 1.13，4.32），但与犬无关（调整后OR 0.98，95%CI 0.95，1.03）。犬使用血液制品与死亡可能性较高相关（OR 3.198，95%CI 1.352，7.565；P = 0.0098），但猫并非如此（OR 1.527，95%CI 0.5404，4.317，P = 0.2）。
设有血液透析单元的兽医医院应能可靠、快速地获取安全的血液制品，以满足接受透析的犬猫的需求。
