Apasov K T, Vanevskiĭ V L
Vestn Khir Im I I Grek. 1987 Apr;138(4):123-7.
Clinical observations in 99 patients and 74 experiments in cats enabled the authors to suggest that nondepolarizing myorelaxants when used in combination affected different portions of cholinergic receptors of the end plate of motor nerves causing greater inhibition of neuromuscular transmission. So an associated simultaneous application of such myorelaxants as tubocurarine and tercuronium as well as tercuronium and Arduan in special sub-blocking doses gives a complete relaxation of skeletal muscles without side effects which allows such methods to be recommended in surgical practice for anesthetic maintenance of operations on high risk patients.
对99例患者的临床观察以及对猫进行的74次实验，使作者提出，非去极化肌松药联合使用时，会影响运动神经终板胆碱能受体的不同部分，从而对神经肌肉传递产生更大抑制作用。因此，将筒箭毒碱和阿曲库铵以及阿曲库铵和阿端等肌松药以特殊的亚阻滞剂量联合同时应用，可使骨骼肌完全松弛且无副作用，这使得这些方法可推荐用于外科手术中高危患者麻醉维持。
