[重症腺病毒肺炎患儿预后不良的危险因素]
[Risk factors for poor prognosis in children with severe adenovirus pneumonia].
作者信息
Huang Miao, Luo Rong, Fu Zhou
机构信息
Deparment of Respiratory Medicine, Children's Hospital of Chongqing Medical University, Chongqing 400014, China.
出版信息
Zhongguo Dang Dai Er Ke Za Zhi. 2017 Feb;19(2):159-162. doi: 10.7499/j.issn.1008-8830.2017.02.006.
OBJECTIVE
To investigate the risk factors for poor prognosis of severe adenovirus pneumonia (SAP) in children.
METHODS
The clinical data of 189 children with SAP were retrospectively analyzed. Univariate logistic regression analysis was performed to assess the risk factors for poor prognosis.
RESULTS
The univariate logistic regression analysis showed that the patients with hemoglobin <90 g/L, plasma albumin <30 g/L, C-reactive protein >30 mg/L, procalcitonin >10 ng/mL, alanine aminotransferase >100 U/L, or aspartate aminotransferase >100 U/L had poor prognosis (P<0.05), and that those with congenital dysplasia of the airway, acute respiratory distress syndrome, circulatory complications, electrolyte and acid-base disturbance, or more than three complications also had poor prognosis (P<0.05).
CONCLUSIONS
Poor prognosis of severe adenovirus pneumonia in children is associated with anemia, low serum albumin, inflammatory response, concurrent multiple complications and underlying lung diseases.
目的
探讨儿童重症腺病毒肺炎（SAP）预后不良的危险因素。
方法
回顾性分析189例SAP患儿的临床资料。采用单因素logistic回归分析评估预后不良的危险因素。
结果
单因素logistic回归分析显示，血红蛋白<90 g/L、血浆白蛋白<30 g/L、C反应蛋白>30 mg/L、降钙素原>10 ng/mL、丙氨酸氨基转移酶>100 U/L或天冬氨酸氨基转移酶>100 U/L的患者预后不良（P<0.05），气道先天性发育不良、急性呼吸窘迫综合征、循环系统并发症、电解质及酸碱紊乱或并发症超过三种的患者预后也不良（P<0.05）。
结论
儿童重症腺病毒肺炎预后不良与贫血、血清白蛋白降低、炎症反应、并发多种并发症及潜在肺部疾病有关。
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