School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation , Wuhan 430030, P. R. China.
Hubei Entry-Exit Inspection and Quarantine Bureau of the PRC, Wuhan 430050, P. R. China.
Org Lett. 2017 Mar 3;19(5):1196-1199. doi: 10.1021/acs.orglett.7b00250. Epub 2017 Feb 16.
Spiroschincarins A-E (1-5), five novel spirocyclic schinortriterpenoids featuring a unique 1-oxaspiro[6.6]tridecane motif, were isolated from the fruit of Schisandra incarnata. Their structures with absolute configurations were determined by extensive spectroscopic analyses, single-crystal X-ray diffractions, and experimental ECD (electronic circular dichroism). A hypothetical biogenetic pathway of 1-5 was postulated.
五味子甲素 - E（1-5），五种新型的螺环环樟烯三萜类化合物，具有独特的 1-氧螺[6.6]十三烷母核，从五味子的果实中分离得到。通过广泛的光谱分析、单晶 X 射线衍射和实验 ECD（电子圆二色性）确定了它们的结构和绝对构型。提出了 1-5 的假设生物合成途径。
