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主胰管自发性破裂与多灶性微小胰腺腺癌同步发生:一例报告

Spontaneous Rupture of the Main Pancreatic Duct Synchronous With a Multi-Focal Microscopic Pancreatic Adenocarcinoma: A Case Report.

作者信息

Shohat Shirly, Shulman Katerina, Kessel Boris, Gal Oren, Zeina Abdel Rauf

机构信息

Faculty, Surgery Division, Hillel Yaffe Medical Center , Hadera, Israel .

Faculty, Oncology Unit, Hillel Yaffe Medical Center , Hadera, Israel .

出版信息

J Clin Diagn Res. 2016 Dec;10(12):PD15-PD17. doi: 10.7860/JCDR/2016/21767.9086. Epub 2016 Dec 1.

DOI:10.7860/JCDR/2016/21767.9086
PMID:28208932
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5296505/
Abstract

Pancreatic cancer is one of the most lethal types of malignant tumours, commonly diagnosed at an advanced stage. The only curative treatment for this fatal disease is surgery and early diagnosis is the key to a better outcome and prognosis. In this case report we present a 57-year-old woman presenting to the emergency room with abdominal pain and weight loss. Computer Tomography (CT) imaging showed a rupture of the main pancreatic duct and a peri-pancreatic fluid collection with no evidence of a pancreatic mass. An Endoscopic Ultrasound (EUS) guided Fine Needle Aspiration (FNA) did not show any malignant cells and Carcinoembryonic Antigen (CEA) and Carbohydrate Antigen (CA) 19-9 markers were in the normal range. The patient then underwent pancreatectomy that revealed multiple microscopic foci of pancreatic adenocarcinoma with evidence of massive perineural and vascular invasion.

摘要

胰腺癌是最致命的恶性肿瘤类型之一,通常在晚期才被诊断出来。对于这种致命疾病,唯一的治愈性治疗方法是手术,而早期诊断是获得更好治疗效果和预后的关键。在本病例报告中,我们介绍了一名57岁女性,她因腹痛和体重减轻前往急诊室就诊。计算机断层扫描(CT)成像显示主胰管破裂和胰周液体积聚,未发现胰腺肿块。内镜超声(EUS)引导下细针穿刺抽吸(FNA)未发现任何恶性细胞,癌胚抗原(CEA)和糖类抗原(CA)19-9标志物在正常范围内。该患者随后接受了胰腺切除术,结果显示有多灶性胰腺腺癌微小病灶,并有大量神经周围和血管侵犯的证据。

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本文引用的文献

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7
CT vs MRCP: optimal classification of IPMN type and extent.CT与磁共振胰胆管造影(MRCP):胰腺导管内乳头状黏液性肿瘤(IPMN)类型及范围的最佳分类
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National failure to operate on early stage pancreatic cancer.国家层面在早期胰腺癌手术治疗方面的不足。
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One thousand consecutive pancreaticoduodenectomies.一千例连续的胰十二指肠切除术。
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