Dillon Alexander B, Sideris Andrew, Hadi Ali, Elbuluk Nada
The Ronald O. Perelman Department of Dermatology, New York University, New York, New York.
J Clin Aesthet Dermatol. 2017 Jan;10(1):15-28. Epub 2017 Jan 1.
Vitiligo is one of the most common cutaneous disorders of depigmentation. Although its underlying causes are still being studied and no definitive cure currently exists, recent research has provided insight into pathogenic mechanisms and new treatment options. The aim of this paper is to provide a comprehensive overview of the medical and surgical therapies for vitiligo with emphasis on the most recent treatment modalities. This review was conducted through a literature search using PubMed and the National institutes of Health's clinicalTrials.gov databases from January 2010 to July 2015. This yielded 86 studies, 12 of which were excluded, and 74 of which were reviewed. Recent studies and ongoing clinical trials indicate that there are many promising new medical and surgical treatment modalities for this chronic condition. A combination of traditional and newer treatments may work synergistically to provide additional improvement in patients' disease state and quality of life.
白癜风是最常见的色素脱失性皮肤病之一。尽管其潜在病因仍在研究中，目前尚无确切的治愈方法，但最近的研究已深入了解其发病机制并提供了新的治疗选择。本文旨在全面概述白癜风的医学和外科治疗方法，重点介绍最新的治疗方式。本综述通过使用PubMed和美国国立卫生研究院的clinicalTrials.gov数据库进行文献检索，检索时间为2010年1月至2015年7月。共获得86项研究，其中12项被排除，74项被纳入综述。最近的研究和正在进行的临床试验表明，对于这种慢性病有许多有前景的新医学和外科治疗方式。传统治疗与新治疗方法相结合可能会产生协同作用，进一步改善患者的病情和生活质量。
