Yagi Taisuke, Hashimoto Daisuke, Taki Katsunobu, Yamamura Kensuke, Chikamoto Akira, Ohmuraya Masaki, Beppu Toru, Baba Hideo
Department of Gastroenterological Surgery, Kumamoto University Graduate School of Medical Sciences, 1-1-1 Honjo, Kumamoto City, 860-8556, Japan.
Department of Gastroenterological Surgery, Institute of Resource Development and Analysis, Kumamoto University Graduate School of Medical Sciences, Kumamoto City, Japan.
Surg Case Rep. 2017 Dec;3(1):31. doi: 10.1186/s40792-017-0308-0. Epub 2017 Feb 18.
Metastatic lesion of the pancreas originated from other organs is uncommon. The aim of this report was to evaluate the outcome of surgery in patients with isolated metastases to the pancreas. Nine patients underwent pancreatic resection for metastatic malignant disease from 2000 to 2015 at the Department of Gastroenterological Surgery of the Kumamoto University Hospital. The primary lesion was renal cell carcinoma in 7 cases, colon cancer in 1 and malignant melanoma in 1. The median interval from the initial operation to pancreatic resection was 138 months. Operative procedure was distal pancreatectomy in 6 cases, pancreaticoduodenectomy in 2 and total pancreatectomy in 1. Two patients with renal cell carcinoma and 1 patient with malignant melanoma died 131, 108, and 4 months after the pancreatic resection, respectively. Other 6 patients have survived until now with 23.5 months of observation periods after pancreatic resection. In conclusion, pancreatic metastasis can develop years after the treatment of primary lesion. Pancreatic resection can achieved long-term survival, at least in the patients who had primary renal carcinoma.
源自其他器官的胰腺转移瘤并不常见。本报告的目的是评估胰腺孤立转移患者的手术结果。2000年至2015年期间，熊本大学医院胃肠外科有9例患者因转移性恶性疾病接受了胰腺切除术。其中7例原发灶为肾细胞癌，1例为结肠癌，1例为恶性黑色素瘤。从初次手术到胰腺切除的中位间隔时间为138个月。手术方式为6例远端胰腺切除术，2例胰十二指肠切除术，1例全胰腺切除术。2例肾细胞癌患者和1例恶性黑色素瘤患者分别在胰腺切除术后131、108和4个月死亡。其他6例患者至今存活，胰腺切除术后的观察期为23.5个月。总之，胰腺转移可在原发灶治疗数年之后发生。胰腺切除术可实现长期生存，至少在原发性肾癌患者中如此。
