Martineau Patrick, Pelletier-Galarneau Matthieu, Zeng Wanzhen
Department of Nuclear Medicine, University of Ottawa, Ottawa, Ontario, Canada.
World J Nucl Med. 2017 Jan-Mar;16(1):71-74. doi: 10.4103/1450-1147.181149.
Erdheim-Chester disease (ECD) is a rare, non-Langerhans histiocytic disorder. The most common manifestations consist of polyostotic sclerotic lesions with the majority of cases also demonstrating soft tissue involvement of the sinuses, retroperitoneum, large vessels, heart, lungs, and central nervous system. Nuclear medicine can play an important role in assessing the extent of the disease with bone scintigraphy and fluorodeoxyglucose (FDG)-positron emission tomography (PET). We present the case of a middle-aged female who initially presented with tooth pain. She subsequently underwent imaging including plain film, bone scan, computed tomography (CT), magnetic resonance imaging (MRI), and FDG-PET/CT, which showed characteristic bony involvement. Biopsy results confirmed the diagnosis of ECD.
厄尔德海姆-切斯特病（ECD）是一种罕见的非朗格汉斯组织细胞增多症。最常见的表现包括多骨硬化性病变，大多数病例还表现为鼻窦、腹膜后、大血管、心脏、肺和中枢神经系统的软组织受累。核医学在通过骨闪烁显像和氟脱氧葡萄糖（FDG）-正电子发射断层扫描（PET）评估疾病范围方面可发挥重要作用。我们报告一例中年女性病例，该患者最初表现为牙痛。随后她接受了包括平片、骨扫描、计算机断层扫描（CT）、磁共振成像（MRI）和FDG-PET/CT在内的影像学检查，这些检查显示出特征性的骨受累情况。活检结果证实为ECD诊断。
