Góis Mário, Azevedo Ariana, Carvalho Fernanda, Nolasco Fernando
Centro Hospitalar de Lisboa Central, Lisboa, Portugal.
BMJ Case Rep. 2017 Feb 20;2017:bcr2016218748. doi: 10.1136/bcr-2016-218748.
Anticoagulant-related nephropathy is a type of acute kidney injury caused by overcoagulation. We describe a case of an 84-year-old man with arterial hypertension, coronary heart disease and atrial fibrillation treated with acenocoumarol, who presented with haematoproteinuria and acute kidney injury during a phase of excessive anticoagulation. In addition to IgA nephropathy, renal biopsy also revealed acute tubular necrosis, red blood cell casts and positive iron staining in tubular cells. After this acute episode, renal function improved and proteinuria decreased below the nephrotic range.
抗凝相关肾病是一种由过度抗凝引起的急性肾损伤。我们描述了一例84岁男性患者，患有动脉高血压、冠心病和心房颤动，正在接受醋硝香豆素治疗，在抗凝过度阶段出现血红蛋白尿和急性肾损伤。肾活检除了发现IgA肾病外，还显示急性肾小管坏死、红细胞管型以及肾小管细胞铁染色阳性。在这次急性发作后，肾功能改善，蛋白尿降至肾病范围以下。
