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本文引用的文献

1
"Asymptomatic" Malaria: A Chronic and Debilitating Infection That Should Be Treated.“无症状”疟疾：一种应予以治疗的慢性衰弱性感染。
PLoS Med. 2016 Jan 19;13(1):e1001942. doi: 10.1371/journal.pmed.1001942. eCollection 2016 Jan.
2
Frequencies of dhfr/dhps multiple mutations and Plasmodium falciparum submicroscopic gametocyte carriage in Gabonese pregnant women following IPTp-SP implementation.在加蓬孕妇中实施间歇性预防治疗（IPTp-SP）后，二氢叶酸还原酶/二氢蝶酸合酶（dhfr/dhps）多重突变的频率及恶性疟原虫亚显微镜配子体携带情况
Acta Parasitol. 2015 Jun;60(2):218-25. doi: 10.1515/ap-2015-0031.
3
Dynamics of the Human Infectious Reservoir for Malaria Determined by Mosquito Feeding Assays and Ultrasensitive Malaria Diagnosis in Burkina Faso.通过布基纳法索的蚊虫叮咬试验和超灵敏疟疾诊断确定的人类疟疾感染储存库动态。
J Infect Dis. 2016 Jan 1;213(1):90-9. doi: 10.1093/infdis/jiv370. Epub 2015 Jul 3.
4
Comparison of detection methods to estimate asexual Plasmodium falciparum parasite prevalence and gametocyte carriage in a community survey in Tanzania.在坦桑尼亚的一项社区调查中，用于估计恶性疟原虫无性寄生虫流行率和配子体携带情况的检测方法比较。
Malar J. 2014 Nov 18;13:433. doi: 10.1186/1475-2875-13-433.
5
Sub-microscopic gametocyte carriage in febrile children living in different areas of Gabon.发热儿童在加蓬不同地区的亚微观配子体携带情况。
Malar J. 2013 Oct 29;12:375. doi: 10.1186/1475-2875-12-375.
6
The changing epidemiology of malaria elimination: new strategies for new challenges.疟疾消除的不断变化的流行病学：新策略应对新挑战。
Lancet. 2013 Sep 7;382(9895):900-11. doi: 10.1016/S0140-6736(13)60310-4. Epub 2013 Apr 15.
7
Increase in malaria prevalence and age of at risk population in different areas of Gabon.加蓬不同地区疟疾发病率和高危人群年龄的增加。
Malar J. 2013 Jan 2;12:3. doi: 10.1186/1475-2875-12-3.
8
Factors determining the occurrence of submicroscopic malaria infections and their relevance for control.决定亚临床疟疾感染发生的因素及其对控制的意义。
Nat Commun. 2012;3:1237. doi: 10.1038/ncomms2241.
9
Association of sub-microscopic malaria parasite carriage with transmission intensity in north-eastern Tanzania.东非坦桑尼亚北部地区亚微观疟原虫携带与传播强度的关系。
Malar J. 2011 Dec 16;10:370. doi: 10.1186/1475-2875-10-370.
10
Evidence of decline of malaria in the general hospital of Libreville, Gabon from 2000 to 2008.2000 年至 2008 年加蓬利伯维尔综合医院疟疾发病率下降的证据。
Malar J. 2009 Dec 17;8:300. doi: 10.1186/1475-2875-8-300.

加蓬城乡发热个体中的亚显微恶性疟原虫感染

Submicroscopic Falciparum Malaria in Febrile Individuals in Urban and Rural Areas of Gabon.

作者信息

Mawili-Mboumba Denise P, Ndong Rosalie Nikiéma, Rosa Noemi Bahamontes, Largo Jose Luis Llergo, Lembet-Mikolo Aude, Nzamba Prycil, Mbouoronde Christelle Offouga, Kombila Maryvonne, Bouyou Akotet Marielle K

机构信息

Malaria Clinical and Operational Research Unit, Libreville, Gabon.

Department of Parasitology-Mycology, Faculty of Medicine, Université des Sciences de la Santé, Libreville, Gabon.

出版信息

Am J Trop Med Hyg. 2017 Apr;96(4):815-818. doi: 10.4269/ajtmh.15-0231. Epub 2017 May 13.

DOI:10.4269/ajtmh.15-0231
PMID:28219989
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5392626/
Abstract

AbstractCharacterization of the parasite reservoir is required to improve malaria control. Asymptomatic patients with subpatent parasitemia have been identified in Gabon, but the prevalence of such infections among febrile subjects is unclear. We assessed the prevalence of submicroscopic infections on an island (Port-Gentil), and in urban (Libreville), semiurban (Melen), and rural (Oyem) settings in Gabon. Blood samples ( = 310) from febrile patients were tested for malaria parasites by quantitative nucleic acid sequence-based amplification (QT-NASBA). Parasites were detected in 55.8% (173/310) of samples by microscopy and in 66.4% (206/310) of samples by 18S rRNA QT-NASBA. The proportion of submicroscopic infections differed considerably between sites. Gametocytes were found in 1% (3/310) of the individuals by microscopy and in 32% (99/310) by mRNA QT-NASBA. Thus, submicroscopic parasitemia is frequent in febrile patients, and the detection of this condition is important, to improve disease control.

摘要

摘要

为了加强疟疾防控，需要对疟原虫储存库进行特征描述。在加蓬已发现存在亚临床疟原虫血症的无症状患者，但发热人群中此类感染的患病率尚不清楚。我们评估了加蓬一个岛屿（让蒂尔港）、城市（利伯维尔）、半城市（梅伦）和农村（奥耶姆）地区亚显微感染的患病率。采用基于核酸序列的定量扩增技术（QT-NASBA）对310例发热患者的血样进行疟原虫检测。显微镜检查在55.8%（173/310）的样本中检测到疟原虫，18S rRNA QT-NASBA在66.4%（206/310）的样本中检测到疟原虫。不同地点亚显微感染的比例差异很大。显微镜检查在1%（3/310）的个体中发现配子体，mRNA QT-NASBA在32%（99/310）的个体中发现配子体。因此，发热患者中亚显微疟原虫血症很常见，检测这种情况对于改善疾病防控很重要。