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印度南部野生亚洲象体内的结核分枝杆菌

Mycobacterium tuberculosis in Wild Asian Elephants, Southern India.

作者信息

Zachariah Arun, Pandiyan Jeganathan, Madhavilatha G K, Mundayoor Sathish, Chandramohan Bathrachalam, Sajesh P K, Santhosh Sam, Mikota Susan K

出版信息

Emerg Infect Dis. 2017 Mar;23(3):504-506. doi: 10.3201/eid2303.161741.

DOI:10.3201/eid2303.161741
PMID:28221104
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5382741/
Abstract

We tested 3 ild Asian elephants (Elephas maximus) in southern India and confirmed infection in 3 animals with Mycobacterium tuberculosis, an obligate human pathogen, by PCR and genetic sequencing. Our results indicate that tuberculosis may be spilling over from humans (reverse zoonosis) and emerging in wild elephants.

摘要

我们在印度南部对3头圈养亚洲象(印度象)进行了检测,通过聚合酶链式反应(PCR)和基因测序,证实这3头大象感染了结核分枝杆菌,这是一种专性人类病原体。我们的结果表明,结核病可能正从人类身上溢出(反向人畜共患病)并在野生大象中出现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0311/5382741/bbc12e653aef/16-1741-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0311/5382741/3f2c1bbf50ba/16-1741-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0311/5382741/bbc12e653aef/16-1741-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0311/5382741/3f2c1bbf50ba/16-1741-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0311/5382741/bbc12e653aef/16-1741-F2.jpg

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Nat Genet. 2013 Oct;45(10):1176-82. doi: 10.1038/ng.2744. Epub 2013 Sep 1.
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First reported case of fatal tuberculosis in a wild African elephant with past human-wildlife contact.首例与人兽接触史相关的野生非洲象致死性肺结核病例报告。
Epidemiol Infect. 2013 Jul;141(7):1476-80. doi: 10.1017/S0950268813000022. Epub 2013 Jan 23.
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Standardization and evaluation of a tetraplex polymerase chain reaction to detect and differentiate Mycobacterium tuberculosis complex and nontuberculous Mycobacteria--a retrospective study on pulmonary TB patients.
亚洲象单核细胞的吞噬功能及流式细胞术表型
Animals (Basel). 2024 Aug 7;14(16):2297. doi: 10.3390/ani14162297.
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Reverse Zoonotic Transmission of SARS-CoV-2 and Monkeypox Virus: A Comprehensive Review.新冠病毒和猴痘病毒的反向人畜共患病传播:全面综述。
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Front Vet Sci. 2023 May 26;10:1133823. doi: 10.3389/fvets.2023.1133823. eCollection 2023.
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