感染猿猴嗜T淋巴细胞病毒I抗体呈血清阳性的大猩猩的慢性致命疾病。
Chronic fatal disease in gorillas seropositive for simian T-lymphotropic virus I antibodies.
作者信息
Blakeslee J R, McClure H M, Anderson D C, Bauer R M, Huff L Y, Olsen R G
机构信息
Department of Veterinary Pathobiology, College of Veterinary Medicine, Ohio State University, Columbus.
出版信息
Cancer Lett. 1987 Oct;37(1):1-6. doi: 10.1016/0304-3835(87)90139-x.
Sera from 10 gorillas were tested by indirect immunofluorescent antibody assay, Western blotting and ELISA to Human T-lymphotropic viruses for cross-reacting with antibodies to Simian T-lymphotropic virus I (STLV-I). Four were antibody positive. Of the 4 seropositive gorillas, one has remained healthy, while 3 have died with similar disease problems as reconstructed from clinical records. It is not known whether a causal relationship exists between these diseases and STLV-I retrovirus infection.
通过间接免疫荧光抗体测定、蛋白质印迹法和酶联免疫吸附测定，对10只大猩猩的血清进行检测，以确定其针对人类嗜T细胞病毒的抗体是否与猿猴嗜T细胞病毒I（STLV-I）抗体发生交叉反应。4只大猩猩抗体呈阳性。在这4只血清反应阳性的大猩猩中，1只一直健康，而另外3只已死亡，根据临床记录推断，它们患有相似的疾病问题。尚不清楚这些疾病与STLV-I逆转录病毒感染之间是否存在因果关系。
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