Issa Claire Michael, Abu Khuzam Rani Hazar
Department of Internal Medicine, Ain Wazein Hospital, El Chouf, Lebanon.
SAGE Open Med Case Rep. 2017 Jan 18;5:2050313X16689209. doi: 10.1177/2050313X16689209. eCollection 2017.
In vitro fertilization is becoming more and more popular lately, as such light is to be shed on any possible related complication. One of these complications is the possible hormonal effect on the lipid profile of the patients.
We present a case of a 39-year-old woman with no prior or family history of dyslipidemia, who presented with post in vitro fertilization severe hypertriglyceridemia and secondary acute pancreatitis and diabetic ketoacidosis. Discussion of the case is followed by a brief review of the literature related to in vitro fertilization-induced hypertriglyceridemia.
This is, up to our knowledge, the sixth reported case of in vitro fertilization-induced hypertriglyceridemia with secondary acute pancreatitis. This is a serious and life-threatening complication. As such, it might be wise at least in high-risk patients (such as patients with diabetes mellitus, polycystic ovaries syndrome, obesity, and family and personal history of dyslipidemia) to screen for lipid abnormalities before initiating in vitro fertilization and monitor these levels afterward.
体外受精近来越来越普遍,因此需要阐明任何可能的相关并发症。其中一种并发症是激素对患者血脂谱的可能影响。
我们呈现一例39岁女性,既往及家族均无血脂异常病史,该患者在体外受精后出现严重高甘油三酯血症、继发性急性胰腺炎和糖尿病酮症酸中毒。病例讨论之后是对与体外受精诱导的高甘油三酯血症相关文献的简要综述。
据我们所知,这是第六例报道的体外受精诱导的高甘油三酯血症伴继发性急性胰腺炎病例。这是一种严重且危及生命的并发症。因此,至少对于高危患者(如糖尿病、多囊卵巢综合征、肥胖以及有血脂异常家族史和个人史的患者),在开始体外受精前筛查血脂异常并在之后监测这些水平可能是明智的。