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体外受精取卵后因高甘油三酯血症诱发的胰腺炎及非诺贝特停药

Hypertriglyceridemia-induced pancreatitis after egg retrieval for in vitro fertilization and fenofibrate cessation.

作者信息

Shrimanker Tushaar V, Retalis Zachary, Hussein Khalil Ian

机构信息

Department of Medicine Greenwich Hospital Yale-New Haven Health System Greenwich Connecticut USA.

出版信息

Clin Case Rep. 2022 May 12;10(5):e05874. doi: 10.1002/ccr3.5874. eCollection 2022 May.

Abstract

A 36-year-old woman with prior hypertriglyceridemia-induced pancreatitis presented with a recurrence of pancreatitis after beginning in vitro fertilization (IVF). Her primary care physician had discontinued fenofibrate due to concerns for teratogenicity. This case illustrates the importance of fibrate therapy for high-risk women undergoing IVF, despite limited evidence regarding its teratogenicity.

摘要

一名36岁既往有高甘油三酯血症性胰腺炎病史的女性,在开始体外受精(IVF)后出现胰腺炎复发。她的初级保健医生因担心致畸性而停用了非诺贝特。该病例说明了贝特类药物治疗对接受IVF的高危女性的重要性,尽管关于其致畸性的证据有限。

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