Rowland Agbara, Benjamin Fomete, Athanasius-Chukwudi Obiadazie, Uchenna-Kevin Omeje, Modupeola-Omotara Samaila
Department of Oral and Maxillofacial Surgery, Jos University Teaching Hospital, Jos, Plateau state, Nigeria.
Department of Oral and Maxillofacial Surgery, Ahmadu Bello University Teaching Hospital, Shika-Zaria, Kaduna state, Nigeria.
Iran J Otorhinolaryngol. 2017 Jan;29(90):35-42.
Myxomas are a group of benign rare tumors of connective-tissue origin that occur in both hard (central) and soft tissues of the body. The aim of this study is to highlight our experience in the management of central myxoma of the jaw, with emphasis on its clinic-epidemiologic features as seen in our environment.
All patients who were managed for central myxoma of the jaw at the Oral and Maxillofacial Surgery department of a regional University Teaching Hospital between September 1997 and October 2015 were retrospectively studied. Details sourced included age, sex, site of tumor, duration, signs/symptoms, treatment given, and complications. Data were analyzed using Statistical Package for Social Sciences (SPSS) version 16 (SPSS Inc., Chicago, IL, USA) and Microsoft Excel 2007 (Microsoft, Redmond, WA, USA). Results from descriptive statistics were represented in the form of tables and charts, with a test for significance ( using Pearson Chi-square (χ) set at 0.05.
A total of 16 patients were managed within the period reviewed, consisting of 10 (62.5%) females and six (37.5%) males, giving a male-to-female ratio of 1:1.7. The ages of patients ranged from 5 to 70 years, with a mean of 27.06±15.45 years. The mandible accounted for nine (56.3%) cases and the maxilla for six (37.5%) cases, while a combination of the maxilla and the zygoma were involved in one (6.3%) case. Bucco-lingual or bucco-palatal expansion were the most common presentation (six [46.2%] cases each). Histological assessment of tissue specimens showed that fibromyxoma accounted for seven (43.8%) cases, while the remaining nine (56.3%) cases were diagnosed as myxoma. All patients had jaw resections, and these consisted of mandibulectomies in nine (60.0%) patients and maxillectomies in six (40.0%) patients. The duration of hospital stay ranged from 5 to 29 days, with a mean of 17.86±7.68 days. Complications were noted in three patients, and all were surgical wound infections.
Most patients in our environment present late with large tumors and are usually not compliant with follow-up review. Thus, a radical approach is favored in most patients.
黏液瘤是一组起源于结缔组织的良性罕见肿瘤，可发生于身体的硬组织（中枢）和软组织。本研究的目的是突出我们在颌骨中枢黏液瘤治疗方面的经验，重点关注在我们所处环境中观察到的其临床流行病学特征。
对1997年9月至2015年10月期间在某地区大学教学医院口腔颌面外科接受颌骨中枢黏液瘤治疗的所有患者进行回顾性研究。收集的详细信息包括年龄、性别、肿瘤部位、病程、体征/症状、所接受的治疗以及并发症。使用社会科学统计软件包（SPSS）16版（美国伊利诺伊州芝加哥市SPSS公司）和Microsoft Excel 2007（美国华盛顿州雷德蒙德市微软公司）对数据进行分析。描述性统计结果以表格和图表形式呈现，显著性检验（使用Pearson卡方检验（χ），设定为0.05）。
在回顾期间共治疗了16例患者，其中女性10例（62.5%），男性6例（37.5%），男女比例为1:1.7。患者年龄范围为5至70岁，平均年龄为27.06±15.45岁。下颌骨占9例（56.3%），上颌骨占6例（37.5%），上颌骨和颧骨联合受累1例（6.3%）。颊舌侧或颊腭侧膨隆是最常见的表现（各6例[46.2%]）。组织标本的组织学评估显示，纤维黏液瘤占7例（43.8%），其余9例（56.3%）诊断为黏液瘤。所有患者均接受了颌骨切除术，其中9例（60.0%）患者行下颌骨切除术，6例（40.0%）患者行上颌骨切除术。住院时间为5至29天，平均为17.86±7.68天。3例患者出现并发症，均为手术伤口感染。
在我们所处环境中，大多数患者就诊时肿瘤较大且通常不配合随访复查。因此，大多数患者倾向于采用根治性方法。
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