Keszler A, Dominguez F V, Giannunzio G
Department of Oral Pathology, Faculty of Dentistry, Buenos Aires University, Argentina.
J Oral Maxillofac Surg. 1995 May;53(5):518-21. doi: 10.1016/0278-2391(95)90062-4.
The object of this study was to present a series of myxoma in children and to evaluate possible differences between young and adults patients.
All tumors of patients under 16 years of age (10 cases), were separated from the 80 myxomas found in the Oral Pathology Laboratory, Faculty of Odontology, Buenos Aires University, and were analyzed in terms of clinical data, radiographic image, histopathology, treatment, and evolution.
Myxoma in childhood represented 12.5% of the 80 cases in our series. The mean age was 11.6 years. Six patients were boys and four were girls. Both jaws were affected equally, predominantly in the premolar-molar region. Eighty percent of the tumors were larger than 2 cm. Only one case was clinically diagnosed as myxoma. Radiologically the most frequent image was unilocular with cortical expansion and tooth displacement. Histologically seven cases were diagnosed as myxoma and three as fibromyxoma. Treatment involved surgical resection in most cases. Two patients showed recurrence within the first year after surgery.
The frequency of myxoma in childhood may be higher than that of other aggressive odontogenic tumors, although some literature refers to this tumor as very uncommon in children. Clinically this tumor may not always be taken into account in the differential diagnosis of intraosseous radiolucencies in young patients. The histologic appearance is similar in young and adult patients, but myxoma in children may be larger. It was not possible to correlate the histologic type of myxoma and the age of the patients.
本研究的目的是呈现一系列儿童黏液瘤病例，并评估儿童患者与成年患者之间可能存在的差异。
从布宜诺斯艾利斯大学牙科学院口腔病理学实验室发现的80例黏液瘤中分离出所有16岁以下患者的肿瘤（10例），并从临床数据、影像学图像、组织病理学、治疗及病情发展等方面进行分析。
儿童黏液瘤占我们系列研究中80例病例的12.5%。平均年龄为11.6岁。6例为男孩，4例为女孩。上下颌受影响程度相同，主要位于前磨牙 - 磨牙区域。80%的肿瘤直径大于2厘米。仅1例临床诊断为黏液瘤。影像学上最常见的表现是单房性伴皮质膨胀和牙齿移位。组织学上，7例诊断为黏液瘤，3例为纤维黏液瘤。大多数病例的治疗方法为手术切除。2例患者在术后第一年内复发。
儿童黏液瘤的发生率可能高于其他侵袭性牙源性肿瘤，尽管一些文献称该肿瘤在儿童中非常罕见。临床上，在年轻患者骨内透光影的鉴别诊断中，该肿瘤可能并非总是被考虑在内。儿童和成年患者的组织学表现相似，但儿童黏液瘤可能更大。无法将黏液瘤的组织学类型与患者年龄相关联。
