Kentner Amanda C, Grace Sherry L
Massachusetts College of Pharmacy and Health Sciences, Health Psychology Program, Boston, MA, United States.
York University, School of Kinesiology and Health Science, Toronto, Ontario, Canada; University Health Network, Toronto General Hospital Research Institute, Peter Munk Cardiac Centre, Toronto, Ontario, Canada; University of Toronto, Faculty of Medicine, Toronto, Ontario, Canada.
Front Neuroendocrinol. 2017 Apr;45:18-24. doi: 10.1016/j.yfrne.2017.02.002. Epub 2017 Feb 21.
Given that both men and women experience cardiovascular disease (CVD), a common misconception is that they have similar risk factors and clinical presentation, receive comparable treatment, and have equivalent clinical outcomes; in reality differences are observed between men and women for each of these endpoints. Moreover, these differences occur as a function of both gender and sex. A review of the literature reveals widespread bias in the selection of research subjects based on these factors, in addition to implicit patient and provider biases that impede the access of women to recommended primary and secondary CVD management. In this perspective, we identify strategies to eliminate such biases and improve women's access to CVD treatments to ensure their care is consistent with current guidelines.
鉴于男性和女性都会患心血管疾病(CVD),一个常见的误解是他们具有相似的风险因素和临床表现,接受类似的治疗,并且有相同的临床结果;但实际上,在这些方面男性和女性之间都存在差异。此外,这些差异是性别和性别的函数。对文献的回顾表明,除了患者和医疗服务提供者的隐性偏见阻碍女性获得推荐的心血管疾病一级和二级管理外,基于这些因素在研究对象选择上也存在广泛的偏见。从这个角度出发,我们确定了消除此类偏见并改善女性获得心血管疾病治疗的策略,以确保她们得到的治疗符合当前指南。