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黎巴嫩年轻成年人群体中的汞健康风险评估。

Mercury health risk assessment among a young adult Lebanese population.

作者信息

Obeid Pierre J, Fares Souha A, Farhat Ghada N, El-Khoury Bilal, Nassif Rana M, El-Nakat John, Dhaini Hassan R

机构信息

Department of Chemistry, University of Balamand, Al Kurah, Balamand, Lebanon.

Hariri School of Nursing, American University of Beirut, Beirut, Lebanon.

出版信息

Environ Sci Pollut Res Int. 2017 Apr;24(10):9370-9378. doi: 10.1007/s11356-017-8621-5. Epub 2017 Feb 23.

Abstract

Mercury (Hg) exposure represents a significant public health concern at a global level. This study aims at assessing Hg exposure and risk among Lebanese young adults based on Hg biomonitoring and seafood intake. A group of 166 young adults were administered a questionnaire to assess Hg exposure and were asked to provide a hair sample. Risk assessment was performed: (1) using the US Environmental Protection Agency Hazard Quotient (HQ) model based on fish intake and previously studied local fish Hg concentrations, and (2) by determining the total hair Hg concentration (THHg) using continuous flow-chemical vapor generation atomic absorption spectrometry. Differences in THHg across demographic and exposure subgroups were tested using t test or ANOVA. Correlations between THHg concentrations, fish consumption, and HQ were determined by computing Pearson's r. Higher THHg correlated with higher consumption of Mediterranean rabbitfish/spinefoots (r = 0.27; p = 0.001) and geographical location (p < 0.001) in the bivariate analysis, and remained significant in the adjusted multivariable linear regression model (geographical location: ß = 0.255, 95%CI 0.121-0.388; rabbitfish/spinefoots consumption: ß = 0.016, 95%CI 0.004-0.027). No significant correlations were found between HQ and THHg. In conclusion, this is the first study examining hair Hg levels and fish consumption in a young adult Lebanese population. Our findings constitute valuable baseline data for a local fish advisory and Hg monitoring.

摘要

汞(Hg)暴露是全球层面一个重大的公共卫生问题。本研究旨在基于汞生物监测和海产品摄入量评估黎巴嫩年轻成年人的汞暴露及风险。对166名年轻成年人进行问卷调查以评估汞暴露情况,并要求他们提供头发样本。进行了风险评估:(1)使用美国环境保护局的危险商数(HQ)模型,该模型基于鱼类摄入量和先前研究的当地鱼类汞浓度;(2)通过使用连续流动化学蒸气发生原子吸收光谱法测定头发总汞浓度(THHg)。使用t检验或方差分析测试不同人口统计学和暴露亚组之间THHg的差异。通过计算Pearson相关系数r来确定THHg浓度、鱼类消费量和HQ之间的相关性。在双变量分析中,较高的THHg与较高的地中海兔头鱼/刺尾鱼消费量(r = 0.27;p = 0.001)和地理位置(p < 0.001)相关,并且在调整后的多变量线性回归模型中仍然显著(地理位置:ß = 0.255,95%CI 0.121 - 0.388;兔头鱼/刺尾鱼消费量:ß = 0.016,95%CI 0.004 - 0.027)。未发现HQ与THHg之间存在显著相关性。总之,这是第一项研究黎巴嫩年轻成年人群体头发汞水平和鱼类消费量的研究。我们的研究结果为当地鱼类咨询和汞监测构成了有价值的基线数据。

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