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单次模拟夜班期间短波耗尽强光能否预防昼夜节律相位偏移?

Can short-wavelength depleted bright light during single simulated night shifts prevent circadian phase shifts?

作者信息

Regente J, de Zeeuw J, Bes F, Nowozin C, Appelhoff S, Wahnschaffe A, Münch M, Kunz D

机构信息

Charité University Medicine, Institute of Physiology, Sleep Research & Clinical Chronobiology, Berlin, Germany; Department of Psychiatry, Psychotherapy and Psychosomatics, Immanuel Clinic Rüdersdorf, Medical School Brandenburg, Rüdersdorf near Berlin, Germany.

Charité University Medicine, Institute of Physiology, Sleep Research & Clinical Chronobiology, Berlin, Germany.

出版信息

Appl Ergon. 2017 May;61:22-30. doi: 10.1016/j.apergo.2016.12.014. Epub 2017 Jan 13.

Abstract

In single night shifts, extending habitual wake episodes leads to sleep deprivation induced decrements of performance during the shift and re-adaptation effects the next day. We investigated whether short-wavelength depleted (=filtered) bright light (FBL) during a simulated night shift would counteract such effects. Twenty-four participants underwent a simulated night shift in dim light (DL) and in FBL. Reaction times, subjective sleepiness and salivary melatonin concentrations were assessed during both nights. Daytime sleep was recorded after both simulated night shifts. During FBL, we found no melatonin suppression compared to DL, but slightly faster reaction times in the second half of the night. Daytime sleep was not statistically different between both lighting conditions (n = 24) and there was no significant phase shift after FBL (n = 11). To conclude, our results showed positive effects from FBL during simulated single night shifts which need to be further tested with larger groups, in more applied studies and compared to standard lighting.

摘要

在单夜班中,延长习惯性清醒时间会导致轮班期间睡眠剥夺引起的绩效下降以及次日的重新适应效应。我们研究了在模拟夜班期间短波耗尽(=过滤)的强光(FBL)是否会抵消此类效应。24名参与者在暗光(DL)和FBL条件下进行了模拟夜班。在两个夜晚期间评估反应时间、主观嗜睡程度和唾液褪黑素浓度。在两个模拟夜班之后记录白天的睡眠情况。在FBL期间,与DL相比,我们未发现褪黑素受到抑制,但在后半夜反应时间略快。两种光照条件下(n = 24)白天的睡眠情况无统计学差异,且FBL后(n = 11)无显著的相位偏移。总之,我们的结果显示了模拟单夜班期间FBL的积极效应,这需要在更多应用研究中使用更大的群体进行进一步测试,并与标准照明进行比较。

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