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光学相干断层扫描血管造影在脉络膜视网膜疾病中的应用

Optical coherence tomography angiography in chorioretinal disorders.

作者信息

De Oliveira Paulo Ricardo Chaves, Berger Alan Richard, Chow David Robert

机构信息

Toronto Retina Institute, Toronto, Ont.

Toronto Retina Institute, Toronto, Ont; Department of Ophthalmology & Vision Sciences, University of Toronto, St. Michael's Hospital, Toronto, Ont.

出版信息

Can J Ophthalmol. 2017 Feb;52(1):125-136. doi: 10.1016/j.jcjo.2016.07.015. Epub 2016 Nov 28.

DOI:10.1016/j.jcjo.2016.07.015
PMID:28237138
Abstract

Optical coherence tomography angiography (OCTA) is a novel imaging modality that incorporates blood motion contrast to create angiograms of the retinal vasculature in a noninvasive manner, without the use of dye. It is a safe procedure and can be repeated as frequently as desired. The use of OCTA for delineation of choroidal neovascular membranes, for the study of microvascular abnormalities in diabetic patients, to assess nonperfused areas in retinal occlusions and vascular changes in macular telangiectasia are some of the potential OCTA applications. However, it is not free of drawbacks. Major limitations include the small field of view and its great sensitivity to movement. As a result, it is prone to motion artifacts, leading to poor-quality images. The scope of the body literature regarding this new modality rapidly increases as we learn how to better use this technology. Our objective is to point overall aspects of OCTA, including its limitations and review some of its initial reports on chorioretinal diseases.

摘要

光学相干断层扫描血管造影(OCTA)是一种新型成像方式,它利用血液流动造影以无创方式生成视网膜血管造影,无需使用染料。这是一种安全的检查方法,可根据需要频繁重复进行。OCTA可用于描绘脉络膜新生血管膜、研究糖尿病患者的微血管异常、评估视网膜阻塞中的无灌注区域以及黄斑毛细血管扩张的血管变化,这些都是OCTA的一些潜在应用。然而,它并非没有缺点。主要局限性包括视野小以及对运动非常敏感。因此,它容易出现运动伪影,导致图像质量不佳。随着我们学会更好地使用这项技术,关于这种新方式的文献数量迅速增加。我们的目的是指出OCTA的总体情况,包括其局限性,并回顾一些关于脉络膜视网膜疾病的初步报告。

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Optical coherence tomography angiography in chorioretinal disorders.光学相干断层扫描血管造影在脉络膜视网膜疾病中的应用
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Parafoveal Microvascular Alterations in Ocular and Non-Ocular Behҫet's Disease Evaluated With Optical Coherence Tomography Angiography.用光学相干断层血管造影术评估眼部和非眼部贝赫切特病的旁中心区微血管改变。
Invest Ophthalmol Vis Sci. 2021 Mar 1;62(3):8. doi: 10.1167/iovs.62.3.8.
2
retinal imaging in translational regenerative research.转化性再生研究中的视网膜成像
Ann Transl Med. 2020 Sep;8(17):1096. doi: 10.21037/atm-20-4355.
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Optical coherence tomography angiography for screening of hydroxychloroquine-induced retinal alterations.
光学相干断层扫描血管造影术用于筛查羟氯喹引起的视网膜病变。
Graefes Arch Clin Exp Ophthalmol. 2018 Nov;256(11):2075-2081. doi: 10.1007/s00417-018-4117-3. Epub 2018 Aug 29.