Ortiz Cristina, Linares Cristina, Carmona Rocio, Díaz Julio
Department of Epidemiology and Biostatistic, National School of Public Health, Carlos III Institute of Health, Madrid, Spain.
Department of Epidemiology and Biostatistic, National School of Public Health, Carlos III Institute of Health, Madrid, Spain.
Environ Pollut. 2017 May;224:541-551. doi: 10.1016/j.envpol.2017.02.037. Epub 2017 Feb 23.
According to the WHO, 3 million deaths are attributable to air pollution due to particulate matter (PM) world-wide. However, there are no specific updated studies which calculate short-term PM-related cause specific mortality in Spain. The objective is to quantify the relative risks (RRs) and attributable risks (ARs) of daily mortality associated with PM concentrations, registered in Spanish provinces and to calculate the number of PM-related deaths. We calculated daily mortality due to natural (ICD-10: A00 R99), circulatory (ICD-10: I00 I99) and respiratory causes (ICD-10: J00 J99) for each province across the period 2000-2009. Mean daily concentrations of PM, NO and O was used. For the estimate of RRs and ARs, we used generalised linear models with a Poisson link. A meta-analysis was used to estimate RRs and ARs in the provinces with statically significant results. The overall RRs obtained for these provinces, corresponding to increases of 10 μ g/m in PM concentrations were 1.009 (95% CI: 1.006 1011) for natural, 1.026 (95% CI: 1.019 1033) for respiratory, and 1.009 (95% CI: 1.006 1012) for circulatory-cause mortality. This amounted to an annual overall total of 2683 deaths (95% CI: 852 4354) due to natural, 651 (95% CI: 359 1026) due to respiratory, and 556 (95% CI: 116 1012) due to circulatory causes, with 90% of this mortality lying below the WHO guideline values. This study provides an updated estimate of the effect had by this type of pollutant on causes of mortality, and constitutes an important basis for reinforcing public health measures.
根据世界卫生组织的数据,全球范围内,300万人的死亡可归因于颗粒物(PM)造成的空气污染。然而,目前尚无具体的最新研究来计算西班牙短期与PM相关的特定病因死亡率。目的是量化西班牙各省登记的与PM浓度相关的每日死亡率的相对风险(RRs)和归因风险(ARs),并计算与PM相关的死亡人数。我们计算了2000年至2009年期间每个省份因自然原因(国际疾病分类第十版:A00 - R99)、循环系统原因(国际疾病分类第十版:I00 - I99)和呼吸系统原因(国际疾病分类第十版:J00 - J99)导致的每日死亡率。使用了PM、NO和O的日均浓度。为了估计RRs和ARs,我们使用了具有泊松链接的广义线性模型。对于具有统计学显著结果的省份,采用荟萃分析来估计RRs和ARs。这些省份对应的PM浓度每增加10μg/m³时获得的总体RRs分别为:自然原因导致的死亡率为1.009(95%置信区间:1.006 - 1.011),呼吸系统原因导致的死亡率为1.026(95%置信区间:1.019 - 1.033),循环系统原因导致的死亡率为1.009(95%置信区间:1.006 - 1.012)。这相当于每年因自然原因导致的死亡总数为2683例(95%置信区间:852 - 4354),因呼吸系统原因导致的死亡为651例(95%置信区间:359 - 1026),因循环系统原因导致的死亡为556例(95%置信区间:116 - 1012),其中90%的死亡率低于世界卫生组织的指导值。本研究提供了此类污染物对死亡率影响的最新估计,是加强公共卫生措施的重要依据。