Pomella Nicola, Wilhelm Eurico Nestor, Kolyva Christina, González-Alonso José, Rakobowchuk Mark, Khir Ashraf W
Institute of Environment, Health and Societies-Biomedical Engineering Research Theme, Brunel University London, Uxbridge, Middlesex, UK.
Centre for Human Performance, Exercise and Rehabilitation, College of Health and Life Sciences, Brunel University London, Uxbridge, Middlesex, UK.
Ultrasound Med Biol. 2017 May;43(5):943-957. doi: 10.1016/j.ultrasmedbio.2016.12.018. Epub 2017 Feb 23.
The aim of this study was to assess the reproducibility of non-invasive, ultrasound-derived wave intensity (WI) in humans at the common carotid artery. Common carotid artery diameter and blood velocity of 12 healthy young participants were recorded at rest and during mild cycling, to assess peak diameter, change in diameter, peak velocity, change in velocity, time derivatives, non-invasive wave speed and WI. Diameter, velocity and WI parameters were fairly reproducible. Diameter variables exhibited higher reproducibility than corresponding velocity variables (intra-class correlation coefficient [ICC] = 0.79 vs. 0.73) and lower dispersion (coefficient of variation [CV] = 5% vs. 9%). Wave speed had fair reproducibility (ICC = 0.6, CV = 16%). WI energy variables exhibited higher reproducibility than corresponding peaks (ICC = 0.78 vs. 0.74) and lower dispersion (CV = 16% vs. 18%). The majority of variables had higher ICCs and lower CVs during exercise. We conclude that non-invasive WI analysis is reliable both at rest and during exercise.
本研究的目的是评估无创超声测量的人体颈总动脉波强度（WI）的可重复性。记录了12名健康年轻参与者在静息状态和轻度骑行期间的颈总动脉直径和血流速度，以评估峰值直径、直径变化、峰值速度、速度变化、时间导数、无创波速和WI。直径、速度和WI参数具有相当高的可重复性。直径变量的可重复性高于相应的速度变量（组内相关系数[ICC]=0.79对0.73），且离散度较低（变异系数[CV]=5%对9%）。波速具有中等可重复性（ICC=0.6，CV=16%）。WI能量变量的可重复性高于相应的峰值（ICC=0.78对0.74），且离散度较低（CV=16%对18%）。大多数变量在运动期间具有更高的ICC和更低的CV。我们得出结论，无创WI分析在静息状态和运动期间都是可靠的。
