Chandrasekharan Anjali, Gandhi Uppal, Badakere Akshay, Sangwan Virender
Department of Paediatric and Neuro-ophthalmology, Child Sight Institute, L V Prasad Eye Institute, Hyderabad, India.
Centre for Ocular Regeneration, L V Prasad Eye Institute, Hyderabad, India.
BMJ Case Rep. 2017 Feb 24;2017:bcr2016217382. doi: 10.1136/bcr-2016-217382.
Orbital apex syndrome is a rare neuro-ophthalmic manifestation of herpes zoster virus infection. We report one such case with favourable outcome in an immunocompetent patient. A 60-year-old woman presented with rash in the dermatome of the left ophthalmic nerve (V1), followed by sudden loss of vision with complete left-sided external and internal ophthalmoplegia. MRI of brain and orbits with contrast revealed optic perineuritis and myositis without intracranial involvement confirming the diagnosis of orbital apex syndrome. Functional visual recovery was achieved after a course of intravenous and oral steroids under antiviral cover over a follow-up period of 3 months.
眶尖综合征是带状疱疹病毒感染罕见的神经眼科表现。我们报告了一例免疫功能正常患者出现该综合征且预后良好的病例。一名60岁女性在左侧眼神经(V1)的皮节出现皮疹,随后突然失明,并伴有完全性左侧眼外肌和眼内肌麻痹。增强头颅和眼眶MRI显示视神经周围炎和肌炎,无颅内受累,确诊为眶尖综合征。在3个月的随访期内,患者在抗病毒治疗的同时接受了一个疗程的静脉和口服类固醇治疗后,视力功能得以恢复。