Jeong In Du
Division of Gastroenterology, Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.
Korean J Gastroenterol. 2017 Feb 25;69(2):96-101. doi: 10.4166/kjg.2017.69.2.96.
The prevalence of gastroesophageal reflux disease (GERD) and the incidence of some of its complications have risen strikingly over the last few decades. With the accumulation in our understanding on the pathophysiology of GERD along with the development of proton pump inhibitors, the diagnostic and therapeutic approaches to the GERD have changed dramatically over the past decade. However, The GERD still poses a problem to many clinicians since the spectrum of the disease has evolved to encompass more challenging presentations such as refractory GERD and extraesophageal manifestations. The aim of this article was to provide a review of available current diagnostic tests of the GERD, includes proton pump inhibitor test, ambulatory pH monitoring, impedance pH monitoring, mucosa impedance, and high resolution manometry. This review discusses different modalities for the work up of GERD.
在过去几十年中，胃食管反流病（GERD）的患病率及其一些并发症的发生率显著上升。随着我们对GERD病理生理学认识的积累以及质子泵抑制剂的发展，过去十年中GERD的诊断和治疗方法发生了巨大变化。然而，GERD仍然给许多临床医生带来问题，因为该疾病的范围已经演变，包括更具挑战性的表现，如难治性GERD和食管外表现。本文的目的是综述目前可用的GERD诊断测试，包括质子泵抑制剂试验、动态pH监测、阻抗pH监测、黏膜阻抗和高分辨率测压法。本综述讨论了GERD检查的不同方式。
