Wang Zao, Cao Xiaoqin, Liu Danni, Hao Shuai, Kong Rongmei, Du Gu, Asiri Abdullah M, Sun Xuping
College of Chemistry, Sichuan University, Chengdu, 610064, Sichuan, China.
College of Chemistry and Chemical Engineering, Qufu Normal University, Qufu, 273165, Shandong, China.
Chemistry. 2017 Apr 11;23(21):4986-4989. doi: 10.1002/chem.201700366. Epub 2017 Mar 23.
It is highly attractive to develop non-noble-metal nanoarray architecture as a 3D-catalyst electrode for molecular detection due to its large specific surface area and easy accessibility to target molecules. Here, we report the development of a copper-nitride nanowires array on copper foam (Cu N NA/CF) as a dual-functional catalyst electrode for efficient glucose oxidation in alkaline solutions and hydrogen peroxide (H O ) reduction in neutral solutions. Electrochemical tests indicate that such Cu N NA/CF possesses superior non-enzymatic sensing ability toward rapid glucose and H O detection with high selectivity. At 0.40 V, this sensor offers a high sensitivity of 14 180 μA mm cm for glucose detection, with a wide linear range from 1 μm to 2 mm, a low detection limit of 13 nm (S/N=3), and satisfactory stability and reproducibility. Its application in determining glucose in human blood serum is also demonstrated. Amperometric H O sensing can also been realized with a sensitivity of 7600 μA mm cm , a linear range from 0.1 μm to 10 mm, and a detection limit of 8.9 nm (S/N=3). This 3D-nanoarray architecture holds great promise as an attractive sensing platform toward electrochemical small molecules detection.
由于其大的比表面积和对目标分子的易接近性，开发非贵金属纳米阵列结构作为用于分子检测的三维催化电极极具吸引力。在此，我们报道了在泡沫铜（Cu N NA/CF）上开发一种氮化铜纳米线阵列，作为一种双功能催化电极，用于在碱性溶液中高效氧化葡萄糖以及在中性溶液中还原过氧化氢（H₂O₂）。电化学测试表明，这种Cu N NA/CF对快速检测葡萄糖和H₂O₂具有优异的非酶传感能力，且选择性高。在0.40 V时，该传感器对葡萄糖检测具有14180 μA·mm⁻²·cm⁻²的高灵敏度，线性范围宽，从1 μm到2 mm，检测限低至13 nm（S/N = 3），并且具有令人满意的稳定性和重现性。还展示了其在测定人血清中葡萄糖的应用。安培法检测H₂O₂也能实现，灵敏度为7600 μA·mm⁻²·cm⁻²，线性范围从0.1 μm到10 mm，检测限为8.9 nm（S/N = 3）。这种三维纳米阵列结构作为一种有吸引力的电化学小分子检测传感平台具有巨大潜力。
