Bégin R O, Cantin A M, Boileau R D, Bisson G Y
Unité de Recherche Pulmonaire, CHUS, Sherbrooke, Québec, Canada.
Chest. 1987 Dec;92(6):1061-7. doi: 10.1378/chest.92.6.1061.
To characterize silica-induced alveolitis in human subjects, we studied 22 workers in the granite stone cutting industry of Quebec and compared results with those of 22 manual workers without quartz exposure (group 1). All were nonsmokers and were of comparable age. On the basis of chest roentgenogram, seven were without disease (group 2), nine had silicosis without coalescence/conglomeration (group 3), and six had silicosis with coalescence/conglomeration (group 4). The alveolitis in subsets of silica-exposed workers with distinct clinical stages of disease was found to have distinct biologic characteristics.
为了描述人类受试者中二氧化硅诱导的肺泡炎，我们研究了魁北克花岗岩切割行业的22名工人，并将结果与22名未接触石英的体力劳动者（第1组）进行了比较。所有受试者均不吸烟且年龄相仿。根据胸部X光片，7人无疾病（第2组），9人患有无融合/聚集的矽肺（第3组），6人患有伴有融合/聚集的矽肺（第4组）。我们发现，处于疾病不同临床阶段的接触二氧化硅的工人亚组中的肺泡炎具有不同的生物学特征。
