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[Detection of cytomegalovirus (CMV) DNA sequence in biopsy samples of cervical cancer].

作者信息

Wang S F, Zhao Y, Fu Q L, Yin M B, Liu Y Y

机构信息

Fourth Hospital, Hebei Medical College, Shijiazhuang.

出版信息

Zhonghua Zhong Liu Za Zhi. 1987 Jul;9(4):279-81.

PMID:2824151
Abstract

Biopsy samples of the cervical cancer and cervicitis were analysed by HCMV-DNA hybridization method. The results indicated that HCMV-DNA was detected in 21 (36%) of 59 cervical cancer and 6 (21%) of 28 cervicitis specimens, using 32P-DNA probe containing transformation gene (14% of total genome) to hybridize. None of 25 cervical cancer and 19 cervicitis samples showed positive HCMV-DNA, using 32P-DNA probe without transformation gene (76% of total genome). The preliminary results show that the sequence of CMV transformation gene is present in about one third of cervical cancer and one fifth of cervicitis biopsy samples tested. This detection rate is lower than that of Taiwan Province and Africa, and slightly higher than that of the USA and Finland. The relation between the HCMV and cervical cancer is being further studied.

摘要

相似文献

1
[Detection of cytomegalovirus (CMV) DNA sequence in biopsy samples of cervical cancer].
Zhonghua Zhong Liu Za Zhi. 1987 Jul;9(4):279-81.
2
[Viral etiology of cancer of the uterine cervix. II. Detection of human cytomegalovirus DNA sequence and antigen in cervical lesions].
Zhonghua Zhong Liu Za Zhi. 1989 Jul;11(4):263-5.
3
Human papillomavirus, human cytomegalovirus and oncogene C-myc in cervical carcinoma and cervicitis.人乳头瘤病毒、人巨细胞病毒及癌基因C-myc与宫颈癌和宫颈炎的关系
Chin Med J (Engl). 1993 Mar;106(3):208-10.
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[Preliminary study on the nucleic acid hybridization technic in detecting HSV-2 DNA corresponding sequence of cancer tissues of the uterine cervix].[核酸杂交技术检测子宫颈癌组织中单纯疱疹病毒Ⅱ型DNA对应序列的初步研究]
Zhonghua Zhong Liu Za Zhi. 1987 Sep;9(5):342-4.
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[Detection of viral DNA homologous sequence in bioptic specimens from patients with cervical carcinoma].[宫颈癌患者活检标本中病毒DNA同源序列的检测]
Zhonghua Yi Xue Za Zhi. 1988 Jul;68(7):387-90, 28.
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Detection of sequences that hybridize to human cytomegalovirus DNA in cervical neoplastic tissue.在宫颈肿瘤组织中检测与人类巨细胞病毒DNA杂交的序列。
Dis Markers. 1986 Oct;4(3):219-29.
7
[Relation between human papillomavirus (HPV) and cancer of uterine cervix].
Zhonghua Zhong Liu Za Zhi. 1987 Nov;9(6):433-5.
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Cytomegalovirus and cervical cancer: failure to detect a direct association or an interaction with human papillomaviruses.巨细胞病毒与宫颈癌：未检测到其与人类乳头瘤病毒的直接关联或相互作用。
Gynecol Oncol. 1994 Jul;54(1):40-6. doi: 10.1006/gyno.1994.1163.
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[Human papillomavirus, human cytomegalovirus and p53 gene in cervical carcinoma].宫颈癌中的人乳头瘤病毒、人巨细胞病毒和p53基因
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