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[Preliminary study on the nucleic acid hybridization technic in detecting HSV-2 DNA corresponding sequence of cancer tissues of the uterine cervix].

作者信息

Cui H Y, Zhang W, Li J, Liu B Y, Li J S, Lin Y C, Zhang W H, Wu A R, Liu Z M

机构信息

Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Beijing.

出版信息

Zhonghua Zhong Liu Za Zhi. 1987 Sep;9(5):342-4.

PMID:2838236
Abstract

In this paper, 34 samples, 25 from 18 cervical carcinoma patients and 9 from 8 non-cervical carcinoma patients, were assayed using (alpha-32P) dCTP HSV-2 DNA probe and nucleic acid hybridization technic. It was shown that the positive rates of HSV-2 DNA corresponding sequence were 50% (2/4), 36% (5/14) and 12% (1/8) in the in situ cancer, invasive cancer and non-cervical cancer tissues. No HSV was isolated from 7 cancer specimens which showed a positive reaction by nucleic acid hybridization.

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