免疫功能正常的成年人因食管憩室念珠菌病引起的顽固性呃逆：一例报告
Intractable hiccups caused by esophageal diverticular candidiasis in an immunocompetent adult: a case report.
作者信息
Yahata Shinsuke, Kenzaka Tsuneaki, Kushida Saeko, Nishisaki Hogara, Akita Hozuka
机构信息
Division of Community Medicine and Career Development, Kobe University Graduate School of Medicine, Kobe; Department of Internal Medicine, Hyogo Prefectural Kaibara Hospital, Tamba.
Division of Community Medicine and Career Development, Kobe University Graduate School of Medicine, Kobe.
出版信息
Int Med Case Rep J. 2017 Feb 10;10:47-50. doi: 10.2147/IMCRJ.S119787. eCollection 2017.
INTRODUCTION
Various causes of intractable hiccups have been reported; however, to the best of our knowledge, there are no previous reports of either intractable hiccups due to esophageal candidiasis in an immunocompetent adult or improvement following antifungal therapy.
CASE PRESENTATION
An 87-year-old man presented with intractable hiccups. Although the patient was immunocompetent, he used proton pump inhibitors. An esophagogastroduodenos-copy revealed several white deposits throughout the esophagus and extensive white deposits in the midesophageal diverticulum. A mucosal culture showed candidiasis, which was suspected to be the cause of the intractable hiccups. After oral fluconazole had been prescribed, the candidiasis resolved and the hiccups improved. Therefore, we concluded that esophageal diverticular candidiasis was the cause of his intractable hiccups.
CONCLUSION
Physicians should consider esophageal candidiasis as one of the differential diagnoses for intractable hiccups, even in immunocompetent adults.
引言
已有多种导致顽固性呃逆的原因被报道；然而，据我们所知，此前尚无关于免疫功能正常的成年人因食管念珠菌病引发顽固性呃逆或抗真菌治疗后病情改善的报道。
病例介绍
一名87岁男性出现顽固性呃逆。尽管该患者免疫功能正常，但他使用质子泵抑制剂。食管胃十二指肠镜检查发现整个食管有多处白色沉积物，食管中段憩室有广泛的白色沉积物。黏膜培养显示念珠菌病，怀疑这是顽固性呃逆的病因。在开具口服氟康唑后，念珠菌病得到缓解，呃逆症状改善。因此，我们得出结论，食管憩室念珠菌病是其顽固性呃逆的病因。
结论
即使对于免疫功能正常的成年人，医生也应将食管念珠菌病作为顽固性呃逆的鉴别诊断之一。
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