Aly Tarek Ahmed
Department of Orthopedic Surgery, Tanta University School of Medicine, Tanta, Egypt.
Asian Spine J. 2017 Feb;11(1):150-160. doi: 10.4184/asj.2017.11.1.150. Epub 2017 Feb 17.
Posterior pedicle screw fixation has become a popular method for treating thoracolumbar burst fractures. However, it remains unclear whether additional fixation of more segments could improve clinical and radiological outcomes. This meta-analysis was performed to evaluate the effectiveness of fixation levels with pedicle screw fixation for thoracolumbar burst fractures. MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials, Springer, and Google Scholar were searched for relevant randomized and quasirandomized controlled trials that compared the clinical and radiological efficacy of short versus long segment for thoracolumbar burst fractures managed by posterior pedicle screw fixation. Risk of bias in included studies was assessed using the Cochrane Risk of Bias tool. Based on predefined inclusion criteria, Nine eligible trials with a total of 365 patients were included in this meta-analysis. Results were expressed as risk difference for dichotomous outcomes and standard mean difference for continuous outcomes with 95% confidence interval. Baseline characteristics were similar between the short and long segment fixation groups. No significant difference was identified between the two groups regarding radiological outcome, functional outcome, neurologic improvement, and implant failure rate. The results of this meta-analysis suggested that extension of fixation was not necessary when thoracolumbar burst fracture was treated by posterior pedicle screw fixation. More randomized controlled trials with high quality are still needed in the future.
后路椎弓根螺钉固定已成为治疗胸腰椎爆裂骨折的常用方法。然而,更多节段的额外固定是否能改善临床和影像学结果仍不清楚。本荟萃分析旨在评估椎弓根螺钉固定节段对胸腰椎爆裂骨折的疗效。检索了MEDLINE、EMBASE、Cochrane对照试验中央注册库、施普林格和谷歌学术,以查找相关的随机和半随机对照试验,这些试验比较了后路椎弓根螺钉固定治疗胸腰椎爆裂骨折时短节段与长节段的临床和影像学疗效。使用Cochrane偏倚风险工具评估纳入研究的偏倚风险。基于预先定义的纳入标准,本荟萃分析纳入了9项符合条件的试验,共365例患者。结果以二分类结局的风险差和连续结局的标准化均数差表示,并给出95%置信区间。短节段和长节段固定组的基线特征相似。两组在影像学结局、功能结局、神经功能改善和内植物失败率方面未发现显著差异。本荟萃分析结果表明,后路椎弓根螺钉固定治疗胸腰椎爆裂骨折时无需延长固定节段。未来仍需要更多高质量的随机对照试验。