Rausch Vanessa Hanna, Bannas Peter, Schoen Gerhard, Froelich Andreas, Well Lennart, Regier Marc, Adam Gerhard, Henes Frank Oliver Gerhard
Department of Diagnostic and Interventional Radiology and Nuclearmedicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Department of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Rofo. 2017 Apr;189(4):339-346. doi: 10.1055/s-0043-101864. Epub 2017 Mar 1.
To determine the value of multidetector computed tomography (MDCT) in patients with acute spondylodiscitis. For data acquisition, we searched our radiological database for all patients who had undergone magnetic resonance imaging (MRI) for suspected spondylodiscitis between 2007 and 2015 (n = 325). For further analyses, we included all patients (n = 67) who initially underwent MDCT prior to MRI. Overall accuracy, sensitivity, specificity and positive and negative predictive values were calculated for MDCT and, separately, for contrast-enhanced CT (CECT, n = 36) and for non-enhanced CT (NECT, n = 31). MRI together with clinical evaluation served as the standard of reference.
In 34 of 43 patients with acute spondylodiscitis on MRI, correct diagnosis was already made by the initial MDCT scan. The specificity and positive predictive value were 100 % for MDCT. The sensitivity was 79 % and the negative predictive value was 72 %. The overall accuracy was 87 %. Accuracy was higher for CECT (89 %) than for NECT (84 %), however without statistical significance (p = 0.55). MDCT detected 90 % of paravertebral abscesses (34/38), but only 6 % of epidural abscesses (2/36). MDCT has moderate sensitivity, but high specificity for acute spondylodiscitis. Thus, if MDCT is positive for spondylodiscitis, treatment can be started without further delay. However, MRI should be added to both MDCT negative and positive cases to rule out complications such as epidural abscesses that cannot reliably be detected by MDCT. · Patients with acute spondylodiscitis are often initially suspected of having other differential diagnosis because of nonspecific symptoms.. · Therefore, MDCT is frequently performed prior to MRI in patients with acute spondylodiscitis.. · MDCT proved moderate sensitivity but high specificity for the diagnosis of acute spondylodiscitis.. · Paravertebral abscess is a strong indicator for the presence of spondylodiscitis on MDCT.. · However, MRI is crucial to rule out epidural abscesses, an important complication.. · Rausch VH, Bannas P, Schoen G et al. Diagnostic Yield of Multidetector Computed Tomography in Patients with Acute Spondylodiscitis. Fortschr Röntgenstr 2017; 189: 339 - 346.
为确定多排螺旋计算机断层扫描(MDCT)在急性脊椎椎间盘炎患者中的价值。对于数据采集,我们在放射学数据库中搜索了2007年至2015年间因疑似脊椎椎间盘炎而接受磁共振成像(MRI)检查的所有患者(n = 325)。为进行进一步分析,我们纳入了所有最初在MRI检查之前接受MDCT检查的患者(n = 67)。计算了MDCT以及分别针对增强CT(CECT,n = 36)和非增强CT(NECT,n = 31)的总体准确性、敏感性、特异性以及阳性和阴性预测值。MRI与临床评估一起作为参考标准。
在MRI诊断为急性脊椎椎间盘炎的43例患者中,有34例通过最初的MDCT扫描已做出正确诊断。MDCT的特异性和阳性预测值为100%。敏感性为79%,阴性预测值为72%。总体准确性为87%。CECT的准确性(89%)高于NECT(84%),但无统计学意义(p = 0.55)。MDCT检测出90%的椎旁脓肿(34/38),但仅检测出6%的硬膜外脓肿(2/36)。MDCT对急性脊椎椎间盘炎具有中等敏感性,但特异性较高。因此,如果MDCT对脊椎椎间盘炎呈阳性,则可立即开始治疗。然而,对于MDCT阴性和阳性的病例都应加做MRI,以排除MDCT无法可靠检测到的并发症,如硬膜外脓肿。·急性脊椎椎间盘炎患者由于症状不具特异性,最初常被怀疑患有其他鉴别诊断疾病。·因此,急性脊椎椎间盘炎患者在MRI检查之前经常进行MDCT检查。·MDCT在诊断急性脊椎椎间盘炎方面证明具有中等敏感性但特异性较高。·椎旁脓肿是MDCT上存在脊椎椎间盘炎的有力指标。·然而,MRI对于排除硬膜外脓肿这一重要并发症至关重要。·劳施VH,班纳斯P,舍恩G等。多排螺旋计算机断层扫描在急性脊椎椎间盘炎患者中的诊断价值。《德国放射学杂志》2017年;189:339 - 346。