Helminen Heli, Luukkaala Tiina, Saarnio Juha, Nuotio Maria
Department of Surgical, Seinäjoki Central Hospital, Seinäjoki, Finland.
Science Center Pirkanmaa Hospital District, Tampere Finland and School of Health Sciences, University of Tampere, Finland.
Injury. 2017 Apr;48(4):903-908. doi: 10.1016/j.injury.2017.02.007. Epub 2017 Feb 22.
Malnutrition is common among older hip fracture patients and associated with adverse outcomes. We examined Mini Nutritional Assessment short (MNA-SF) and long form (MNA-LF) and serum albumin as prognostic indicators of mobility, living arrangements and mortality after hip fracture.
Population-based prospective data were collected on 594 hip fracture patients aged 65 and over. MNA-SF, MNA-LF and serum albumin were assessed on admission. Outcomes were poorer mobility; transfer to more assisted living accommodation and mortality one month, four months and one year post fracture. Logistic regression analyses for mobility and living arrangements with odds ratios (OR) and Cox proportional hazards model for mortality with hazard ratios (HR) and 95% confidence intervals (CI) were used, adjusted for age, gender, ASA grade and fracture type.
All measures predicted mortality at all time-points. Risk of malnutrition and malnutrition measured by MNA-LF predicted mobility and living arrangements within four months of hip fracture. At one year, risk of malnutrition predicted mobility and malnutrition predicted living arrangements, when measured by MNA-LF. Malnutrition, but not risk thereof, measured by MNA-SF predicted living arrangements at all time-points. None of the measures predicted one-month mobility.
All measures were strong indicators of short- and long-term mortality after hip fracture. MNA-LF was superior in predicting mobility and living arrangements, particularly at four months. All measures were relatively poor in predicting short-term outcomes of mobility and living arrangements.
营养不良在老年髋部骨折患者中很常见,且与不良预后相关。我们研究了微型营养评定简表(MNA-SF)、长表(MNA-LF)以及血清白蛋白作为髋部骨折后活动能力、居住安排和死亡率的预后指标。
收集了594名65岁及以上髋部骨折患者基于人群的前瞻性数据。入院时评估MNA-SF、MNA-LF和血清白蛋白。结局指标为较差的活动能力;转至更多辅助生活设施以及骨折后1个月、4个月和1年的死亡率。采用逻辑回归分析活动能力和居住安排,计算比值比(OR),采用Cox比例风险模型分析死亡率,计算风险比(HR)和95%置信区间(CI),并对年龄、性别、美国麻醉医师协会(ASA)分级和骨折类型进行校正。
所有指标均能预测各时间点的死亡率。MNA-LF所衡量的营养不良风险和营养不良状况可预测髋部骨折后4个月内的活动能力和居住安排。1年后,MNA-LF所衡量的营养不良风险可预测活动能力,营养不良状况可预测居住安排。MNA-SF所衡量的营养不良状况(而非其风险)可预测所有时间点的居住安排。所有指标均无法预测1个月时的活动能力。
所有指标均是髋部骨折后短期和长期死亡率的有力指标。MNA-LF在预测活动能力和居住安排方面更具优势,尤其是在4个月时。所有指标在预测活动能力和居住安排的短期结局方面相对较差。